New Insights into How the Rho Guanine Nucleotide Dissociation Inhibitor Regulates the Interaction of Cdc42 with Membranes

by Johnson, Jared L., Erickson, Jon W., Cerione, Richard A.
Published 2009

C-terminal Di-arginine Motif of Cdc42 Protein Is Essential for Binding to Phosphatidylinositol 4,5-Bisphosphate-containing Membranes and Inducing Cellular Transformation

by Johnson, Jared L., Erickson, Jon W., Cerione, Richard A.
Published 2012

Interactions between epigenetics and metabolism in cancers

by Yun, Jihye, Johnson, Jared L., Hanigan, Christin L., Locasale, Jason W.
Published 2012

Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7

by Zhou, Yeyun, Johnson, Jared L., Cerione, Richard A., Erickson, Jon W.
Published 2013

A Unique Role for Heat Shock Protein 70 and Its Binding Partner Tissue Transglutaminase in Cancer Cell Migration

by Boroughs, Lindsey K., Antonyak, Marc A., Johnson, Jared L., Cerione, Richard A.
Published 2011

Regulation of folate and methionine metabolism by multisite phosphorylation of human methylenetetrahydrofolate reductase

by Zheng, Yuxiang, Ramsamooj, Shivan, Li, Qian, Johnson, Jared L., Yaron, Tomer M., Sharra, Klaus, Cantley, Lewis C.
Published in Sci Rep (2019)

Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors

by Robert, Thomas, Johnson, Jared L., Guichaoua, Roxane, Yaron, Tomer M., Bach, Stéphane, Cantley, Lewis C., Colas, Pierre
Published in Front Chem (2020)

Mapping Post-Translational Modifications of de Novo Purine Biosynthetic Enzymes: Implications for Pathway Regulation

by Liu, Chunliang, Knudsen, Giselle M., Pedley, Anthony M., He, Jingxuan, Johnson, Jared L., Yaron, Tomer M., Cantley, Lewis C., Benkovic, Stephen J.
Published in J Proteome Res (2019)

Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells

by Antonyak, Marc A., Li, Bo, Boroughs, Lindsey K., Johnson, Jared L., Druso, Joseph E., Bryant, Kirsten L., Holowka, David A., Cerione, Richard A.
Published 2011

Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1)

by Balasuriya, Nileeka, Davey, Norman E., Johnson, Jared L., Liu, Huadong, Biggar, Kyle K., Cantley, Lewis C., Li, Shawn Shun-Cheng, O'Donoghue, Patrick
Published in J Biol Chem (2020)

EGF receptor specificity for phosphotyrosine-primed substrates provides signal integration with Src

by Begley, Michael J, Yun, Cai-hong, Gewinner, Christina A, Asara, John M, Johnson, Jared L, Coyle, Anthony J, Eck, Michael J, Apostolou, Irina, Cantley, Lewis C
Published in Nat Struct Mol Biol (2015)

Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry

by Kastenhuber, Edward R., Jaimes, Javier A., Johnson, Jared L., Mercadante, Marisa, Muecksch, Frauke, Weisblum, Yiska, Bram, Yaron, Schwartz, Robert E., Whittaker, Gary R., Cantley, Lewis C.
Published in bioRxiv (2021)

Human primary immunodeficiency caused by expression of a kinase-dead p110δ mutant

by Cohen, Sarah Beaussant, Bainter, Wayne, Johnson, Jared L., Lin, Ting-Yu, Wong, Jenny C.Y., Wallace, Jacqueline, Jones, Jennifer, Mir, Fatima, Qamar, Farah, Cantley, Lewis C., Geha, Raif S., Chou, Janet
Published in J Allergy Clin Immunol (2018)

The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation

by Lee, Ho-Soo, Lin, Zhonghui, Chae, Sunyoung, Yoo, Young-Suk, Kim, Byung-Gyu, Lee, Youngsoo, Johnson, Jared L., Kim, You-Sun, Cantley, Lewis C., Lee, Chang-Woo, Yu, Hongtao, Cho, Hyeseong
Published in Nat Commun (2018)

Discovery of covalent CDK14 inhibitors with pan-TAIRE family specificity

by Ferguson, Fleur M., Doctor, Zainab M., Ficarro, Scott B., Browne, Christopher M., Marto, Jarrod A., Johnson, Jared L., Yaron, Tomer M., Cantley, Lewis C., Kim, Nam Doo, Sim, Taebo, Berberich, Matthew J., Kalocsay, Marian, Sorger, Peter, Gray, Nathanael S.
Published in Cell Chem Biol (2019)

A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification

by Browne, Christopher M., Jiang, Baishan, Ficarro, Scott B., Doctor, Zainab M., Johnson, Jared L., Card, Joseph D., Sivakumaren, Sindhu Carmen, Alexander, William M., Yaron, Tomer M., Murphy, Charles J., Kwiatkowski, Nicholas P., Zhang, Tinghu, Cantley, Lewis C., Gray, Nathanael S., Marto, Jarrod A.
Published in J Am Chem Soc (2018)

Phosphatidylinositol-5-phosphate 4-kinases regulate cellular lipid metabolism by facilitating autophagy

by Lundquist, Mark R., Goncalves, Marcus D., Loughran, Ryan M., Possik, Elite, Vijayaraghavan, Tarika, Yang, Annan, Pauli, Chantal, Ravi, Archna, Verma, Akanksha, Yang, Zhiwei, Johnson, Jared L., Wong, Jenny C.Y., Ma, Yilun, Hwang, Katie Seo-Kyoung, Weinkove, David, Divecha, Nullin, Asara, John M., Elemento, Olivier, Rubin, Mark A., Kimmelman, Alec C., Pause, Arnim, Cantley, Lewis C., Emerling, Brooke M.
Published in Mol Cell (2018)

Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors

by Vasan, Neil, Razavi, Pedram, Johnson, Jared L., Shao, Hong, Shah, Hardik, Antoine, Alesia, Ladewig, Erik, Gorelick, Alexander, Lin, Ting-Yu, Toska, Eneda, Xu, Guotai, Kazmi, Abiha, Chang, Matthew T., Taylor, Barry S., Dickler, Maura N., Jhaveri, Komal, Chandarlapaty, Sarat, Rabadan, Raul, Reznik, Ed, Smith, Melissa L., Sebra, Robert, Schimmoller, Frauke, Wilson, Timothy R., Friedman, Lori S., Cantley, Lewis C., Scaltriti, Maurizio, Baselga, José
Published in Science (2019)

Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids

by Han, Yuling, Yang, Liuliu, Duan, Xiaohua, Duan, Fuyu, Nilsson-Payant, Benjamin E., Yaron, Tomer M., Wang, Pengfei, Tang, Xuming, Zhang, Tuo, Zhao, Zeping, Bram, Yaron, Redmond, David, Houghton, Sean, Nguyen, Duc, Xu, Dong, Wang, Xing, Uhl, Skyler, Huang, Yaoxing, Johnson, Jared L., Xiang, Jenny, Wang, Hui, Pan, Fong Cheng, Cantley, Lewis C., tenOever, Benjamin R., Ho, David D., Evans, Todd, Schwartz, Robert E., Chen, Huanhuan Joyce, Chen, Shuibing
Published in bioRxiv (2020)

Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription

by Rimel, Jenna K., Poss, Zachary C., Erickson, Benjamin, Maas, Zachary L., Ebmeier, Christopher C., Johnson, Jared L., Decker, Tim-Michael, Yaron, Tomer M., Bradley, Michael J., Hamman, Kristin B., Hu, Shanhu, Malojcic, Goran, Marineau, Jason J., White, Peter W., Brault, Martine, Tao, Limei, DeRoy, Patrick, Clavette, Christian, Nayak, Shraddha, Damon, Leah J., Kaltheuner, Ines H., Bunch, Heeyoun, Cantley, Lewis C., Geyer, Matthias, Iwasa, Janet, Dowell, Robin D., Bentley, David L., Old, William M., Taatjes, Dylan J.
Published in Genes Dev (2020)