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C-terminal Di-arginine Motif of Cdc42 Protein Is Essential for Binding to Phosphatidylinositol 4,5-Bisphosphate-containing Membranes and Inducing Cellular Transformation

Rho GTPases regulate a diverse range of processes that are dependent on their proper cellular localization. The membrane localization of these GTPases is due in large part to their carboxyl-terminal geranylgeranyl moiety. In addition, most of the Rho family members contain a cluster of positively ch...

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Bibliografiset tiedot
Päätekijät: Johnson, Jared L., Erickson, Jon W., Cerione, Richard A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325590/
https://ncbi.nlm.nih.gov/pubmed/22215673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.336487
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