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The two splice variant forms of Cdc42 exert distinct and essential functions in neurogenesis

The small GTPase cell division cycle 42 (CDC42) plays essential roles in neurogenesis and brain development. Previously, using murine embryonic P19 cells as a model system, we showed that CDC42 stimulates mTOR complex 1 (mTORC1) activity and thereby up-regulates transcription factors required for th...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Endo, Makoto, Druso, Joseph E., Cerione, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136000/
https://ncbi.nlm.nih.gov/pubmed/32071086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011837
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