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The two splice variant forms of Cdc42 exert distinct and essential functions in neurogenesis

The small GTPase cell division cycle 42 (CDC42) plays essential roles in neurogenesis and brain development. Previously, using murine embryonic P19 cells as a model system, we showed that CDC42 stimulates mTOR complex 1 (mTORC1) activity and thereby up-regulates transcription factors required for th...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Endo, Makoto, Druso, Joseph E., Cerione, Richard A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136000/
https://ncbi.nlm.nih.gov/pubmed/32071086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011837
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