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The two splice variant forms of Cdc42 exert distinct and essential functions in neurogenesis

The small GTPase cell division cycle 42 (CDC42) plays essential roles in neurogenesis and brain development. Previously, using murine embryonic P19 cells as a model system, we showed that CDC42 stimulates mTOR complex 1 (mTORC1) activity and thereby up-regulates transcription factors required for th...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Endo, Makoto, Druso, Joseph E., Cerione, Richard A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136000/
https://ncbi.nlm.nih.gov/pubmed/32071086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011837
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