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The two splice variant forms of Cdc42 exert distinct and essential functions in neurogenesis
The small GTPase cell division cycle 42 (CDC42) plays essential roles in neurogenesis and brain development. Previously, using murine embryonic P19 cells as a model system, we showed that CDC42 stimulates mTOR complex 1 (mTORC1) activity and thereby up-regulates transcription factors required for th...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7136000/ https://ncbi.nlm.nih.gov/pubmed/32071086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011837 |
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