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Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7

The unconventional Guanine Nucleotide Exchange Factor (GEF) family comprising 11 DOCK180 related proteins is classified into four subfamilies, A through D, based on their relative GEF activity towards the closely related Rac and Cdc42 GTPases. DOCK proteins participate in the remodeling of the actin...

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Detalhes bibliográficos
Main Authors: Zhou, Yeyun, Johnson, Jared L., Cerione, Richard A., Erickson, Jon W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752685/
https://ncbi.nlm.nih.gov/pubmed/23718289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301688g
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