New Insights into How the Rho Guanine Nucleotide Dissociation Inhibitor Regulates the Interaction of Cdc42 with Membranes

gan Johnson, Jared L., Erickson, Jon W., Cerione, Richard A.
Cyhoeddwyd 2009

C-terminal Di-arginine Motif of Cdc42 Protein Is Essential for Binding to Phosphatidylinositol 4,5-Bisphosphate-containing Membranes and Inducing Cellular Transformation

gan Johnson, Jared L., Erickson, Jon W., Cerione, Richard A.
Cyhoeddwyd 2012

Interactions between epigenetics and metabolism in cancers

gan Yun, Jihye, Johnson, Jared L., Hanigan, Christin L., Locasale, Jason W.
Cyhoeddwyd 2012

Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7

gan Zhou, Yeyun, Johnson, Jared L., Cerione, Richard A., Erickson, Jon W.
Cyhoeddwyd 2013

A Unique Role for Heat Shock Protein 70 and Its Binding Partner Tissue Transglutaminase in Cancer Cell Migration

gan Boroughs, Lindsey K., Antonyak, Marc A., Johnson, Jared L., Cerione, Richard A.
Cyhoeddwyd 2011

Regulation of folate and methionine metabolism by multisite phosphorylation of human methylenetetrahydrofolate reductase

gan Zheng, Yuxiang, Ramsamooj, Shivan, Li, Qian, Johnson, Jared L., Yaron, Tomer M., Sharra, Klaus, Cantley, Lewis C.
Cyhoeddwyd yn Sci Rep (2019)

Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors

gan Robert, Thomas, Johnson, Jared L., Guichaoua, Roxane, Yaron, Tomer M., Bach, Stéphane, Cantley, Lewis C., Colas, Pierre
Cyhoeddwyd yn Front Chem (2020)

Mapping Post-Translational Modifications of de Novo Purine Biosynthetic Enzymes: Implications for Pathway Regulation

gan Liu, Chunliang, Knudsen, Giselle M., Pedley, Anthony M., He, Jingxuan, Johnson, Jared L., Yaron, Tomer M., Cantley, Lewis C., Benkovic, Stephen J.
Cyhoeddwyd yn J Proteome Res (2019)

Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells

gan Antonyak, Marc A., Li, Bo, Boroughs, Lindsey K., Johnson, Jared L., Druso, Joseph E., Bryant, Kirsten L., Holowka, David A., Cerione, Richard A.
Cyhoeddwyd 2011

Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1)

gan Balasuriya, Nileeka, Davey, Norman E., Johnson, Jared L., Liu, Huadong, Biggar, Kyle K., Cantley, Lewis C., Li, Shawn Shun-Cheng, O'Donoghue, Patrick
Cyhoeddwyd yn J Biol Chem (2020)

EGF receptor specificity for phosphotyrosine-primed substrates provides signal integration with Src

gan Begley, Michael J, Yun, Cai-hong, Gewinner, Christina A, Asara, John M, Johnson, Jared L, Coyle, Anthony J, Eck, Michael J, Apostolou, Irina, Cantley, Lewis C
Cyhoeddwyd yn Nat Struct Mol Biol (2015)

Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry

gan Kastenhuber, Edward R., Jaimes, Javier A., Johnson, Jared L., Mercadante, Marisa, Muecksch, Frauke, Weisblum, Yiska, Bram, Yaron, Schwartz, Robert E., Whittaker, Gary R., Cantley, Lewis C.
Cyhoeddwyd yn bioRxiv (2021)

Human primary immunodeficiency caused by expression of a kinase-dead p110δ mutant

gan Cohen, Sarah Beaussant, Bainter, Wayne, Johnson, Jared L., Lin, Ting-Yu, Wong, Jenny C.Y., Wallace, Jacqueline, Jones, Jennifer, Mir, Fatima, Qamar, Farah, Cantley, Lewis C., Geha, Raif S., Chou, Janet
Cyhoeddwyd yn J Allergy Clin Immunol (2018)

The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation

gan Lee, Ho-Soo, Lin, Zhonghui, Chae, Sunyoung, Yoo, Young-Suk, Kim, Byung-Gyu, Lee, Youngsoo, Johnson, Jared L., Kim, You-Sun, Cantley, Lewis C., Lee, Chang-Woo, Yu, Hongtao, Cho, Hyeseong
Cyhoeddwyd yn Nat Commun (2018)

Discovery of covalent CDK14 inhibitors with pan-TAIRE family specificity

gan Ferguson, Fleur M., Doctor, Zainab M., Ficarro, Scott B., Browne, Christopher M., Marto, Jarrod A., Johnson, Jared L., Yaron, Tomer M., Cantley, Lewis C., Kim, Nam Doo, Sim, Taebo, Berberich, Matthew J., Kalocsay, Marian, Sorger, Peter, Gray, Nathanael S.
Cyhoeddwyd yn Cell Chem Biol (2019)

A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification

gan Browne, Christopher M., Jiang, Baishan, Ficarro, Scott B., Doctor, Zainab M., Johnson, Jared L., Card, Joseph D., Sivakumaren, Sindhu Carmen, Alexander, William M., Yaron, Tomer M., Murphy, Charles J., Kwiatkowski, Nicholas P., Zhang, Tinghu, Cantley, Lewis C., Gray, Nathanael S., Marto, Jarrod A.
Cyhoeddwyd yn J Am Chem Soc (2018)

Phosphatidylinositol-5-phosphate 4-kinases regulate cellular lipid metabolism by facilitating autophagy

gan Lundquist, Mark R., Goncalves, Marcus D., Loughran, Ryan M., Possik, Elite, Vijayaraghavan, Tarika, Yang, Annan, Pauli, Chantal, Ravi, Archna, Verma, Akanksha, Yang, Zhiwei, Johnson, Jared L., Wong, Jenny C.Y., Ma, Yilun, Hwang, Katie Seo-Kyoung, Weinkove, David, Divecha, Nullin, Asara, John M., Elemento, Olivier, Rubin, Mark A., Kimmelman, Alec C., Pause, Arnim, Cantley, Lewis C., Emerling, Brooke M.
Cyhoeddwyd yn Mol Cell (2018)

Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors

gan Vasan, Neil, Razavi, Pedram, Johnson, Jared L., Shao, Hong, Shah, Hardik, Antoine, Alesia, Ladewig, Erik, Gorelick, Alexander, Lin, Ting-Yu, Toska, Eneda, Xu, Guotai, Kazmi, Abiha, Chang, Matthew T., Taylor, Barry S., Dickler, Maura N., Jhaveri, Komal, Chandarlapaty, Sarat, Rabadan, Raul, Reznik, Ed, Smith, Melissa L., Sebra, Robert, Schimmoller, Frauke, Wilson, Timothy R., Friedman, Lori S., Cantley, Lewis C., Scaltriti, Maurizio, Baselga, José
Cyhoeddwyd yn Science (2019)

Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids

gan Han, Yuling, Yang, Liuliu, Duan, Xiaohua, Duan, Fuyu, Nilsson-Payant, Benjamin E., Yaron, Tomer M., Wang, Pengfei, Tang, Xuming, Zhang, Tuo, Zhao, Zeping, Bram, Yaron, Redmond, David, Houghton, Sean, Nguyen, Duc, Xu, Dong, Wang, Xing, Uhl, Skyler, Huang, Yaoxing, Johnson, Jared L., Xiang, Jenny, Wang, Hui, Pan, Fong Cheng, Cantley, Lewis C., tenOever, Benjamin R., Ho, David D., Evans, Todd, Schwartz, Robert E., Chen, Huanhuan Joyce, Chen, Shuibing
Cyhoeddwyd yn bioRxiv (2020)

Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription

gan Rimel, Jenna K., Poss, Zachary C., Erickson, Benjamin, Maas, Zachary L., Ebmeier, Christopher C., Johnson, Jared L., Decker, Tim-Michael, Yaron, Tomer M., Bradley, Michael J., Hamman, Kristin B., Hu, Shanhu, Malojcic, Goran, Marineau, Jason J., White, Peter W., Brault, Martine, Tao, Limei, DeRoy, Patrick, Clavette, Christian, Nayak, Shraddha, Damon, Leah J., Kaltheuner, Ines H., Bunch, Heeyoun, Cantley, Lewis C., Geyer, Matthias, Iwasa, Janet, Dowell, Robin D., Bentley, David L., Old, William M., Taatjes, Dylan J.
Cyhoeddwyd yn Genes Dev (2020)