Mapping Post-Translational Modifications of de Novo Purine Biosynthetic Enzymes: Implications for Pathway Regulation

Purines represent a class of essential metabolites produced by the cell to maintain cellular homeostasis and facilitate cell proliferation. In times of high purine demand, the de novo purine biosynthetic pathway is activated; however, the mechanisms that facilitate this process are largely unknown....

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Bibliographic Details
Published in:J Proteome Res
Main Authors: Liu, Chunliang, Knudsen, Giselle M., Pedley, Anthony M., He, Jingxuan, Johnson, Jared L., Yaron, Tomer M., Cantley, Lewis C., Benkovic, Stephen J.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499638/
https://ncbi.nlm.nih.gov/pubmed/30964683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00969
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