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Expression of the purine biosynthetic enzyme phosphoribosyl formylglycinamidine synthase (FGAMS) in neurons

Purines are metabolic building blocks essential for all living organisms on earth. De novo purine biosynthesis occurs in the brain and appears to play important roles in neural development. Phosphoribosyl formylglycinamidine synthase (FGAMS, also known as PFAS or FGARAT), a core enzyme involved in t...

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Bibliografiske detaljer
Udgivet i:J Neurochem
Main Authors: Mangold, Colleen A., Yao, Pamela J., Du, Mei, Freeman, Willard M., Benkovic, Stephen J., Szpara, Moriah L.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942248/
https://ncbi.nlm.nih.gov/pubmed/29337348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14304
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