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Human de novo Purine Biosynthesis

The focus of this review is the human de novo purine biosynthetic pathway. The pathway enzymes are enumerated, as well as the reactions they catalyze and their physical properties. Early literature evidence suggested that they might assemble into a multi-enzyme complex called a metabolon. The findin...

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Bibliographic Details
Published in:Crit Rev Biochem Mol Biol
Main Authors: Pareek, Vidhi, Pedley, Anthony M., Benkovic, Stephen J.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7869020/
https://ncbi.nlm.nih.gov/pubmed/33179964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2020.1832438
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