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Metabolomics and mass spectrometry imaging reveal channeled de novo purine synthesis in cells
Metabolons, multiprotein complexes consisting of sequential enzymes of a metabolic pathway, are proposed to be biosynthetic “hotspots” within the cell. However, experimental demonstration of their presence and functions has remained challenging. We used metabolomics and in situ three-dimensional sub...
Tallennettuna:
| Julkaisussa: | Science |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7494208/ https://ncbi.nlm.nih.gov/pubmed/32299949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz6465 |
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