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Quantitative Detection of Purines in Biologically-Relevant Films with TOF-Secondary Ion Mass Spectrometry
In purine-depleted environments, the de novo purine biosynthetic pathway is catalyzed to ultimately produce inosine monophosphate (IMP), a purine invisible using current optical microscopy methodology. These enzymes form a complex, termed the “purinosome,” to replenish IMP levels. Before cellular ch...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4084853/ https://ncbi.nlm.nih.gov/pubmed/25009363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sia.5098 |
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