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Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer

Cancer cells exhibit altered metabolism including aerobic glycolysis that channels several glycolytic intermediates into de novo purine biosynthetic pathway. We discovered increased expression of phosphoribosyl amidotransferase (PPAT) and phosphoribosylaminoimidazole carboxylase, phosphoribosylamino...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: Goswami, Moloy T., Chen, Guoan, Chakravarthi, Balabhadrapatruni V.S.K., Pathi, Satya S., Anand, Sharath K., Carskadon, Shannon L., Giordano, Thomas J., Chinnaiyan, Arul M., Thomas, Dafydd G., Palanisamy, Nallasivam, Beer, David G., Varambally, Sooryanarayana
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695129/
https://ncbi.nlm.nih.gov/pubmed/26140362
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