PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer

The identification of colorectal cancer (CRC) molecular targets is needed for the development of drugs that improve patient survival. We investigated the functional role of phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), a de novo purine...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Agarwal, Sumit, Chakravarthi, Balabhadrapatruni V. S. K., Behring, Michael, Kim, Hyung-Gyoon, Chandrashekar, Darshan S., Gupta, Nirzari, Bajpai, Prachi, Elkholy, Amr, Balasubramanya, Sai A. H., Hardy, Cherlene, Diffalha, Sameer Al, Varambally, Sooryanarayana, Manne, Upender
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226071/
https://ncbi.nlm.nih.gov/pubmed/32218208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040772
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