PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer

The identification of colorectal cancer (CRC) molecular targets is needed for the development of drugs that improve patient survival. We investigated the functional role of phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), a de novo purine...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Agarwal, Sumit, Chakravarthi, Balabhadrapatruni V. S. K., Behring, Michael, Kim, Hyung-Gyoon, Chandrashekar, Darshan S., Gupta, Nirzari, Bajpai, Prachi, Elkholy, Amr, Balasubramanya, Sai A. H., Hardy, Cherlene, Diffalha, Sameer Al, Varambally, Sooryanarayana, Manne, Upender
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226071/
https://ncbi.nlm.nih.gov/pubmed/32218208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040772
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