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PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer

The identification of colorectal cancer (CRC) molecular targets is needed for the development of drugs that improve patient survival. We investigated the functional role of phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), a de novo purine...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Agarwal, Sumit, Chakravarthi, Balabhadrapatruni V. S. K., Behring, Michael, Kim, Hyung-Gyoon, Chandrashekar, Darshan S., Gupta, Nirzari, Bajpai, Prachi, Elkholy, Amr, Balasubramanya, Sai A. H., Hardy, Cherlene, Diffalha, Sameer Al, Varambally, Sooryanarayana, Manne, Upender
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226071/
https://ncbi.nlm.nih.gov/pubmed/32218208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040772
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