Reconstructing the Hsp90/Tau Machine

Por Jinwal, Umesh K., Koren, John, Dickey, Chad A.
Publicado em 2013

Data from SILAC-based quantitative analysis of lysates from mouse microglial cells treated with Withaferin A (WA)

Por Narayan, Malathi, Seeley, Kent W., Jinwal, Umesh K.
Publicado no Data Brief (2016)

Natural products as a rich source of tau-targeting drugs for Alzheimer’s disease

Por Calcul, Laurent, Zhang, Bo, Jinwal, Umesh K, Dickey, Chad A, Baker, Bill J
Publicado em 2012

Bending tau into shape: the emerging role of peptidyl prolyl-isomerases in tauopathies

Por Koren, John, Jinwal, Umesh K., Davey, Zachary, Kiray, Janine, Arulselvam, Karthik, Dickey, Chad A.
Publicado em 2011

Identification of Dihydropyridines That Reduce Cellular Tau Levels

Por Evans, Christopher G., Jinwal, Umesh K., Makley, Leah N., Dickey, Chad A., Gestwicki, Jason E.
Publicado em 2010

Allosteric drugs: the interaction of anti-tumor compound MKT-077 with human Hsp70 chaperones

Por Rousaki, Aikaterini, Miyata, Yoshi, Jinwal, Umesh K., Dickey, Chad A., Gestwicki, Jason E., Zuiderweg, Erik R.P.
Publicado em 2011

Exploiting the Diversity of the Heat-Shock Protein Family for Primary and Secondary Tauopathy Therapeutics

Por Abisambra, Jose F, Jinwal, Umesh K, Jones, Jeffrey R, Blair, Laura J, Koren, John, Dickey, Chad A
Publicado em 2011

Hsp70 ATPase Modulators as Therapeutics for Alzheimer’s and other Neurodegenerative Diseases

Por Jinwal, Umesh K., Koren, John, O’Leary, John C., Jones, Jeffrey R., Abisambra, Jose F., Dickey, Chad A.
Publicado em 2010

Cysteine Reactivity Distinguishes Redox Sensing by the Heat Inducible and Constitutive Forms of Heat Shock Protein 70 (Hsp70)

Por Miyata, Yoshinari, Rauch, Jennifer N., Jinwal, Umesh K., Thompson, Andrea D., Srinivasan, Sharan, Dickey, Chad A., Gestwicki, Jason E.
Publicado em 2012

Targeting gene expression to the female larval fat body of transgenic Aedes aegypti mosquitoes

Por TOTTEN, Daniel C., VUONG, Mai, LITVINOVA, Oksana V., JINWAL, Umesh K., GULIA-NUSS, Monika, HARRELL, Robert A., BENEŠ, Helen
Publicado em 2012

DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau

Por Abisambra, Jose F., Jinwal, Umesh K., Suntharalingam, Amirthaa, Arulselvam, Karthik, Brady, Sarah, Cockman, Mattew, Jin, Ying, Zhang, Bo, Dickey, Chad A.
Publicado em 2012

Chaperone signalling complexes in Alzheimer's disease

Por Koren, John, Jinwal, Umesh K, Lee, Daniel C, Jones, Jeffrey R, Shults, Cody L, Johnson, Amelia G, Anderson, Laura J, Dickey, Chad A
Publicado em 2009

The coupling of epidermal growth factor receptor down regulation by 1alpha,25-dihydroxyvitamin D3 to the hormone-induced cell cycle arrest at the G1-S checkpoint in ovarian cancer...

Por Shen, Zheng, Zhang, Xiaohui, Tang, Jinfu, Kasiappan, Ravi, Jinwal, Umesh, Li, Pengfei, Hann, Shan, Nicosia, Santo V., Wu, Jie, Zhang, Xiaohong, Bai, Wenlong
Publicado em 2011

Analysis of the Tau-Associated Proteome Reveals that Exchange of Hsp70 for Hsp90 Is Involved in Tau Degradation

Por Thompson, Andrea D., Scaglione, K. Matthew, Prensner, John, Gillies, Anne T., Chinnaiyan, Arul, Paulson, Henry L., Jinwal, Umesh K., Dickey, Chad A., Gestwicki, Jason E.
Publicado em 2012

Adeno-Associated Virus-Mediated Rescue of the Cognitive Defects in a Mouse Model for Angelman Syndrome

Por Daily, Jennifer L., Nash, Kevin, Jinwal, Umesh, Golde, Todd, Rogers, Justin, Peters, Melinda M., Burdine, Rebecca D., Dickey, Chad, Banko, Jessica L., Weeber, Edwin J.
Publicado em 2011

1,25-Dihydroxyvitamin D3 Suppresses Telomerase Expression and Human Cancer Growth through MicroRNA-498

Por Kasiappan, Ravi, Shen, Zheng, Tse, Anfernee K-W, Jinwal, Umesh, Tang, Jinfu, Lungchukiet, Panida, Sun, Yuefeng, Kruk, Patricia, Nicosia, Santo V., Zhang, Xiaohong, Bai, Wenlong
Publicado em 2012

Cdc37/Hsp90 Protein Complex Disruption Triggers an Autophagic Clearance Cascade for TDP-43 Protein

Por Jinwal, Umesh K., Abisambra, Jose F., Zhang, Juan, Dharia, Sheetal, O'Leary, John C., Patel, Tina, Braswell, Kaitlyn, Jani, Twisha, Gestwicki, Jason E., Dickey, Chad A.
Publicado em 2012

Aging Analysis Reveals Slowed Tau Turnover and Enhanced Stress Response in a Mouse Model of Tauopathy

Por Dickey, Chad, Kraft, Clara, Jinwal, Umesh, Koren, John, Johnson, Amelia, Anderson, Laura, Lebson, Lori, Lee, Daniel, Dickson, Dennis, de Silva, Rohan, Binder, Lester I., Morgan, David, Lewis, Jada
Publicado em 2009

Synthesis and Initial Evaluation of YM-08, a Blood-Brain Barrier Permeable Derivative of the Heat Shock Protein 70 (Hsp70) Inhibitor MKT-077, Which Reduces Tau Levels

Por Miyata, Yoshinari, Li, Xiaokai, Lee, Hsiu-Fang, Jinwal, Umesh K., Srinivasan, Sharan R., Seguin, Sandlin P., Young, Zapporah T., Brodsky, Jeffrey L., Dickey, Chad A., Sun, Duxin, Gestwicki, Jason E.
Publicado em 2013

Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance

Por Koren, John, Miyata, Yoshinari, Kiray, Janine, O'Leary, John C., Nguyen, Lana, Guo, Jianping, Blair, Laura J., Li, Xiokai, Jinwal, Umesh K., Cheng, Jin Q., Gestwicki, Jason E., Dickey, Chad A.
Publicado em 2012