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Identification of Dihydropyridines That Reduce Cellular Tau Levels
A series of dihydropyridines were identified that have an effect on the accumulation of tau, an important target in Alzheimer's disease. The dihydropyridine collection was expanded using the Hantzsch multicomponent reaction to develop preliminary structure-activity relationships.
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251959/ https://ncbi.nlm.nih.gov/pubmed/21082080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc02253e |
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