Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

BACKGROUND: It has traditionally been thought that the pathological accumulation of tau in Alzheimer's disease and other tauopathies facilitates neurodegeneration, which in turn leads to cognitive impairment. However, recent evidence suggests that tau tangles are not the entity responsible for...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: O'Leary, John C, Li, Qingyou, Marinec, Paul, Blair, Laura J, Congdon, Erin E, Johnson, Amelia G, Jinwal, Umesh K, Koren, John, Jones, Jeffrey R, Kraft, Clara, Peters, Melinda, Abisambra, Jose F, Duff, Karen E, Weeber, Edwin J, Gestwicki, Jason E, Dickey, Chad A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989315/
https://ncbi.nlm.nih.gov/pubmed/21040568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-45
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados