Recent Advances in Development and Application of Physiologically-Based Pharmacokinetic (PBPK) Models: a Transition from Academic Curiosity to Regulatory Acceptance

Bằng Jamei, Masoud
Xuất bản năm Curr Pharmacol Rep (2016)

Where Do PBPK Models Stand in Pharmacometrics and Systems Pharmacology?

Bằng Jamei, Masoud
Xuất bản năm CPT Pharmacometrics Syst Pharmacol (2020)

Simulation of Monoclonal Antibody Pharmacokinetics in HumansUsing a Minimal Physiologically Based Model

Bằng Li, Linzhong, Gardner, Iain, Dostalek, Miroslav, Jamei, Masoud
Được phát hành 2014

A Bottom-Up Whole-Body Physiologically Based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins

Bằng Gill, Katherine L., Gardner, Iain, Li, Linzhong, Jamei, Masoud
Xuất bản năm AAPS J (2015)

Changes in Individual Drug-Independent System Parameters during Virtual Paediatric Pharmacokinetic Trials: Introducing Time-Varying Physiology into a Paediatric PBPK Model

Bằng Abduljalil, Khaled, Jamei, Masoud, Rostami-Hodjegan, Amin, Johnson, Trevor N.
Được phát hành 2014

Application of Physiologically Based Pharmacokinetic (PBPK) Modeling Within a Bayesian Framework to Identify Poor Metabolizers of Efavirenz (PM), Using a Test Dose of Efavirenz

Bằng Chetty, Manoranjenni, Cain, Theresa, Wedagedera, Janak, Rostami-Hodjegan, Amin, Jamei, Masoud
Xuất bản năm Front Pharmacol (2018)

Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling to Predict the Impact of CYP2C9 Genetic Polymorphisms, Co-Medication and Formulation on the Pharmacokinetics and Phar...

Bằng Loisios-Konstantinidis, Ioannis, Cristofoletti, Rodrigo, Jamei, Masoud, Turner, David, Dressman, Jennifer
Xuất bản năm Pharmaceutics (2020)

A pregnancy physiologically based pharmacokinetic (p-PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4

Bằng Gaohua, Lu, Abduljalil, Khaled, Jamei, Masoud, Johnson, Trevor N, Rostami-Hodjegan, Amin
Được phát hành 2012

Considerations and Caveats when Applying Global Sensitivity Analysis Methods to Physiologically Based Pharmacokinetic Models

Bằng Liu, Dan, Li, Linzhong, Rostami-Hodjegan, Amin, Bois, Frederic Y., Jamei, Masoud
Xuất bản năm AAPS J (2020)

Are Physiologically Based Pharmacokinetic Models Reporting the Right C(max)? Central Venous Versus Peripheral Sampling Site

Bằng Musther, Helen, Gill, Katherine L., Chetty, Manoranjenni, Rostami-Hodjegan, Amin, Rowland, Malcolm, Jamei, Masoud
Xuất bản năm AAPS J (2015)

Quantitative approach for cardiac risk assessment and interpretation in tuberculosis drug development

Bằng Polak, Sebastian, Romero, Klaus, Berg, Alexander, Patel, Nikunjkumar, Jamei, Masoud, Hermann, David, Hanna, Debra
Xuất bản năm J Pharmacokinet Pharmacodyn (2018)

Population-Based Mechanistic Prediction of Oral Drug Absorption

Bằng Jamei, Masoud, Turner, David, Yang, Jiansong, Neuhoff, Sibylle, Polak, Sebastian, Rostami-Hodjegan, Amin, Tucker, Geoffrey
Được phát hành 2009

The Simcyp Population Based Simulator: Architecture, Implementation, and Quality Assurance

Bằng Jamei, Masoud, Marciniak, Steve, Edwards, Duncan, Wragg, Kris, Feng, Kairui, Barnett, Adrian, Rostami-Hodjegan, Amin
Xuất bản năm In Silico Pharmacol (2013)

Prediction of the Pharmacokinetics, Pharmacodynamics, and Efficacy of a Monoclonal Antibody, Using a Physiologically Based Pharmacokinetic FcRn Model

Bằng Chetty, Manoranjenni, Li, Linzhong, Rose, Rachel, Machavaram, Krishna, Jamei, Masoud, Rostami-Hodjegan, Amin, Gardner, Iain
Xuất bản năm Front Immunol (2015)

Does age affect gastric emptying time? A model‐based meta‐analysis of data from premature neonates through to adults

Bằng Bonner, Jennifer J., Vajjah, Pavan, Abduljalil, Khaled, Jamei, Masoud, Rostami‐Hodjegan, Amin, Tucker, Geoffrey T., Johnson, Trevor N.
Xuất bản năm Biopharm Drug Dispos (2015)

Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug conc...

Bằng Chetty, Manoranjenni, Rose, Rachel H., Abduljalil, Khaled, Patel, Nikunjkumar, Lu, Gaohua, Cain, Theresa, Jamei, Masoud, Rostami-Hodjegan, Amin
Xuất bản năm Front Pharmacol (2014)

Developing Clinically Relevant Dissolution Specifications for Oral Drug Products—Industrial and Regulatory Perspectives

Bằng McAllister, Mark, Flanagan, Talia, Boon, Karin, Pepin, Xavier, Tistaert, Christophe, Jamei, Masoud, Abend, Andreas, Kotzagiorgis, Evangelos, Mackie, Claire
Xuất bản năm Pharmaceutics (2019)

Pharmacokinetics under the COVID‐19 storm

Bằng Pilla Reddy, Venkatesh, El‐Khateeb, Eman, Jo, Heeseung, Giovino, Natalie, Lythgoe, Emily, Sharma, Shringi, Tang, Weifeng, Jamei, Masoud, Rastomi‐Hodjegan, Amin
Xuất bản năm Br J Clin Pharmacol (2021)

Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model

Bằng Almond, Lisa M., Mukadam, Sophie, Gardner, Iain, Okialda, Krystle, Wong, Susan, Hatley, Oliver, Tay, Suzanne, Rowland-Yeo, Karen, Jamei, Masoud, Rostami-Hodjegan, Amin, Kenny, Jane R.
Xuất bản năm Drug Metab Dispos (2016)

Physiologically Based Pharmacokinetic Model Qualification and Reporting Procedures for Regulatory Submissions: A Consortium Perspective

Bằng Shebley, Mohamad, Sandhu, Punam, Emami Riedmaier, Arian, Jamei, Masoud, Narayanan, Rangaraj, Patel, Aarti, Peters, Sheila Annie, Reddy, Venkatesh Pilla, Zheng, Ming, de Zwart, Loeckie, Beneton, Maud, Bouzom, Francois, Chen, Jun, Chen, Yuan, Cleary, Yumi, Collins, Christiane, Dickinson, Gemma L., Djebli, Nassim, Einolf, Heidi J., Gardner, Iain, Huth, Felix, Kazmi, Faraz, Khalil, Feras, Lin, Jing, Odinecs, Aleksandrs, Patel, Chirag, Rong, Haojing, Schuck, Edgar, Sharma, Pradeep, Wu, Shu‐Pei, Xu, Yang, Yamazaki, Shinji, Yoshida, Kenta, Rowland, Malcolm
Xuất bản năm Clin Pharmacol Ther (2018)