Application of Physiologically Based Pharmacokinetic (PBPK) Modeling Within a Bayesian Framework to Identify Poor Metabolizers of Efavirenz (PM), Using a Test Dose of Efavirenz

Por Chetty, Manoranjenni, Cain, Theresa, Wedagedera, Janak, Rostami-Hodjegan, Amin, Jamei, Masoud
Publicado no Front Pharmacol (2018)

Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model I: Insights into Factors that Determine Fetal Drug Exposure through Simulations and Sensitivity An...

Por Zhang, Zufei, Imperial, Marjorie Z., Patilea-Vrana, Gabriela I., Wedagedera, Janak, Gaohua, Lu, Unadkat, Jashvant D.
Publicado no Drug Metab Dispos (2017)