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Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model I: Insights into Factors that Determine Fetal Drug Exposure through Simulations and Sensitivity Analyses
Determining fetal drug exposure (except at the time of birth) is not possible for both logistical and ethical reasons. Therefore, we developed a novel maternal-fetal physiologically based pharmacokinetic (m-f-PBPK) model to predict fetal exposure to drugs and populated this model with gestational ag...
সংরক্ষণ করুন:
| প্রকাশিত: | Drug Metab Dispos |
|---|---|
| প্রধান লেখক: | , , , , , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5506457/ https://ncbi.nlm.nih.gov/pubmed/28588050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.075192 |
| ট্যাগগুলো: |
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