Structural Biology of Presenilins and Signal Peptide Peptidases

Por Tomita, Taisuke, Iwatsubo, Takeshi
Publicado em 2013

Presenilins and γ-Secretase: Structure, Function, and Role in Alzheimer Disease

Por De Strooper, Bart, Iwatsubo, Takeshi, Wolfe, Michael S.
Publicado em 2012

Presenilin-dependent intramembrane cleavage of ephrin-B1

Por Tomita, Taisuke, Tanaka, Sayaka, Morohashi, Yuichi, Iwatsubo, Takeshi
Publicado em 2006

Seeded Aggregation and Toxicity of α-Synuclein and Tau: CELLULAR MODELS OF NEURODEGENERATIVE DISEASES

Por Nonaka, Takashi, Watanabe, Sayuri T., Iwatsubo, Takeshi, Hasegawa, Masato
Publicado em 2010

Contribution of the γ-Secretase Subunits to the Formation of Catalytic Pore of Presenilin 1 Protein

Por Takeo, Koji, Watanabe, Naoto, Tomita, Taisuke, Iwatsubo, Takeshi
Publicado em 2012

Phosphorylation of α-Synuclein Protein at Ser-129 Reduces Neuronal Dysfunction by Lowering Its Membrane Binding Property in Caenorhabditis elegans

Por Kuwahara, Tomoki, Tonegawa, Reina, Ito, Genta, Mitani, Shohei, Iwatsubo, Takeshi
Publicado em 2012

Lack of Correlation between the Kinase Activity of LRRK2 Harboring Kinase-Modifying Mutations and Its Phosphorylation at Ser910, 935, and Ser955

Por Ito, Genta, Fujimoto, Tetta, Kamikawaji, Shogo, Kuwahara, Tomoki, Iwatsubo, Takeshi
Publicado em 2014

Role of Apolipoprotein E in β-Amyloidogenesis: ISOFORM-SPECIFIC EFFECTS ON PROTOFIBRIL TO FIBRIL CONVERSION OF Aβ IN VITRO AND BRAIN Aβ DEPOSITION IN VIVO

Por Hori, Yukiko, Hashimoto, Tadafumi, Nomoto, Hidetoshi, Hyman, Bradley T., Iwatsubo, Takeshi
Publicado no J Biol Chem (2015)

Imago Mundi, Imago AD, Imago ADNI

Por Villemagne, Victor L, Kim, Seong Yoon, Rowe, Christopher C, Iwatsubo, Takeshi
Publicado no Alzheimers Res Ther (2014)

Amyloid Angiopathy and Variability in Amyloid β Deposition Is Determined by Mutation Position in Presenilin-1-Linked Alzheimer’s Disease

Por Mann, David M. A., Pickering-Brown, Stuart M., Takeuchi, Ayano, Iwatsubo, Takeshi
Publicado em 2001

Sample Size Estimation for Alzheimer’s Disease Trials from Japanese ADNI Serial Magnetic Resonance Imaging

Por Fujishima, Motonobu, Kawaguchi, Atsushi, Maikusa, Norihide, Kuwano, Ryozo, Iwatsubo, Takeshi, Matsuda, Hiroshi
Publicado no J Alzheimers Dis (2017)

Ku70 Alleviates Neurodegeneration in Drosophila Models of Huntington's Disease

Por Tamura, Takuya, Sone, Masaki, Iwatsubo, Takeshi, Tagawa, Kazuhiko, Wanker, Erich E., Okazawa, Hitoshi
Publicado em 2011

Correction: Ku70 Alleviates Neurodegeneration in Drosophila Models of Huntington's Disease

Por Tamura, Takuya, Sone, Masaki, Iwatsubo, Takeshi, Tagawa, Kazuhiko, Wanker, Erich E., Okazawa, Hitoshi
Publicado em 2012

AMPA-R Removal Underlies Aβ-induced Synaptic Depression and Dendritic Spine Loss

Por Hsieh, Helen, Boehm, Jannic, Sato, Chihiro, Iwatsubo, Takeshi, Tomita, Taisuke, Sisodia, Sangram, Malinow, Roberto
Publicado em 2006

Comparison of Presenilin 1 and Presenilin 2 γ-Secretase Activities Using a Yeast Reconstitution System

Por Yonemura, Yoji, Futai, Eugene, Yagishita, Sosuke, Suo, Satoshi, Tomita, Taisuke, Iwatsubo, Takeshi, Ishiura, Shoichi
Publicado em 2011

Phantom criteria for qualification of brain FDG and amyloid PET across different cameras

Por Ikari, Yasuhiko, Akamatsu, Go, Nishio, Tomoyuki, Ishii, Kenji, Ito, Kengo, Iwatsubo, Takeshi, Senda, Michio
Publicado no EJNMMI Phys (2016)

Hsp104 antagonizes α-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease

Por Lo Bianco, Christophe, Shorter, James, Régulier, Etienne, Lashuel, Hilal, Iwatsubo, Takeshi, Lindquist, Susan, Aebischer, Patrick
Publicado em 2008

Biochemical Characterization of the Drosophila Wingless Signaling Pathway Based on RNA Interference

Por Matsubayashi, Hiroko, Sese, Sonoka, Lee, Jong-Seo, Shirakawa, Tadaoki, Iwatsubo, Takeshi, Tomita, Taisuke, Yanagawa, Shin-ichi
Publicado em 2004

Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an α-synuclein rat model of Parkinson's disease

Por Lo Bianco, Christophe, Schneider, Bernard L., Bauer, Matthias, Sajadi, Ali, Brice, Alexis, Iwatsubo, Takeshi, Aebischer, Patrick
Publicado em 2004

FTY720/Fingolimod, a Sphingosine Analogue, Reduces Amyloid-β Production in Neurons

Por Takasugi, Nobumasa, Sasaki, Tomoki, Ebinuma, Ihori, Osawa, Satoko, Isshiki, Hayato, Takeo, Koji, Tomita, Taisuke, Iwatsubo, Takeshi
Publicado em 2013