Pathogenesis/genetics of frontotemporal dementia and how it relates to ALS

by Bennion Callister, Janis, Pickering-Brown, Stuart M.
Published in Exp Neurol (2014)

Amyloid Angiopathy and Variability in Amyloid β Deposition Is Determined by Mutation Position in Presenilin-1-Linked Alzheimer’s Disease

by Mann, David M. A., Pickering-Brown, Stuart M., Takeuchi, Ayano, Iwatsubo, Takeshi
Published 2001

Modelling C9orf72 dipeptide repeat proteins of a physiologically relevant size

by Bennion Callister, Janis, Ryan, Sarah, Sim, Joan, Rollinson, Sara, Pickering-Brown, Stuart M.
Published in Hum Mol Genet (2016)

The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43

by Hicks, David A., Jones, Alys C., Pickering-Brown, Stuart M., Hooper, Nigel M.
Published in Biosci Rep (2020)

Expression of C9orf72-related dipeptides impairs motor function in a vertebrate model

by Swaminathan, Amrutha, Bouffard, Marilou, Liao, Meijiang, Ryan, Sarah, Callister, Janis Bennion, Pickering-Brown, Stuart M, Armstrong, Gary Alan Barclay, Drapeau, Pierre
Published in Hum Mol Genet (2018)

Extracellular Vesicles Isolated from Human Induced Pluripotent Stem Cell-Derived Neurons Contain a Transcriptional Network

by Hicks, David A., Jones, Alys C., Corbett, Nicola J., Fisher, Kate, Pickering-Brown, Stuart M., Ashe, Mark P., Hooper, Nigel M.
Published in Neurochem Res (2020)

TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer’s disease and frontotemporal lobar degeneration

by Foulds, Penelope, McAuley, Erica, Gibbons, Linda, Davidson, Yvonne, Pickering-Brown, Stuart M., Neary, David, Snowden, Julie S., Allsop, David, Mann, David M. A.
Published 2008

Plasma levels of progranulin and interleukin-6 in frontotemporal lobar degeneration

by Gibbons, Linda, Rollinson, Sara, Thompson, Jennifer C., Robinson, Andrew, Davidson, Yvonne S., Richardson, Anna, Neary, David, Pickering-Brown, Stuart M., Snowden, Julie S., Mann, David M.A.
Published in Neurobiol Aging (2015)

Parietal Lobe Deficits in Frontotemporal Lobar Degeneration Caused by a Mutation in the Progranulin Gene

by Rohrer, Jonathan D, Warren, Jason D, Omar, Rohani, Mead, Simon, Beck, Jonathan, Revesz, Tamas, Holton, Janice, Stevens, John M, Al-Sarraj, Safa, Pickering-Brown, Stuart M, Hardy, John, Fox, Nick C, Collinge, John, Warrington, Elizabeth K, Rossor, Martin N
Published 2008

Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations

by Snowden, Julie S., Rollinson, Sara, Thompson, Jennifer C., Harris, Jennifer M., Stopford, Cheryl L., Richardson, Anna M. T., Jones, Matthew, Gerhard, Alex, Davidson, Yvonne S., Robinson, Andrew, Gibbons, Linda, Hu, Quan, DuPlessis, Daniel, Neary, David, Mann, David M. A., Pickering-Brown, Stuart M.
Published 2012

A small deletion in C9orf72 hides a proportion of expansion carriers in FTLD

by Rollinson, Sara, Bennion Callister, Janis, Young, Kate, Ryan, Sarah J., Druyeh, Ronald, Rohrer, Jonathan D., Snowden, Julie, Richardson, Anna, Jones, Matt, Harris, Jenny, Davidson, Yvonne, Robinson, Andrew, Ealing, John, Johnson, Janel O., Traynor, Bryan, Mead, Simon, Mann, David, Pickering-Brown, Stuart M.
Published in Neurobiol Aging (2015)

Ubiquitin Associated Protein 1 is a risk factor for frontotemporal lobar degeneration

by Rollinson, Sara, Rizzu, Patrizia, Sikkink, Stephen, Baker, Matthew, Halliwell, Nicola, Snowden, Julie, Traynor, Bryan J, Ruano, Dina, Cairns, Nigel, Rohrer, Jonathan D., Mead, Simon, Collinge, John, Rossor, Martin, Akay, Ela, Guerreiro, Rita, Rademakers, Rosa, Morrison, Karen E, Pastor, Pau, Alonso, Elena, Martinez-Lage, Pablo, Graff-Radford, Neil, Neary, David, Heutink, Peter, Mann, David MA, Swieten, John Van, Pickering-Brown, Stuart M
Published 2009

Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease

by Schott, Jonathan M., Crutch, Sebastian J., Carrasquillo, Minerva M., Uphill, James, Shakespeare, Tim J., Ryan, Natalie S., Yong, Keir X., Lehmann, Manja, Ertekin-Taner, Nilufer, Graff-Radford, Neill R., Boeve, Bradley F., Murray, Melissa E., Khan, Qurat ul Ain, Petersen, Ronald C., Dickson, Dennis W., Knopman, David S., Rabinovici, Gil D., Miller, Bruce L., González, Aida Suárez, Gil-Néciga, Eulogio, Snowden, Julie S., Harris, Jenny, Pickering-Brown, Stuart M., Louwersheimer, Eva, van der Flier, Wiesje M., Scheltens, Philip, Pijnenburg, Yolande A., Galasko, Douglas, Sarazin, Marie, Dubois, Bruno, Magnin, Eloi, Galimberti, Daniela, Scarpini, Elio, Cappa, Stefano F., Hodges, John R., Halliday, Glenda M., Bartley, Lauren, Carrillo, Maria C., Bras, Jose T., Hardy, John, Rossor, Martin N., Collinge, John, Fox, Nick C., Mead, Simon
Published in Alzheimers Dement (2016)

FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration

by Urwin, Hazel, Josephs, Keith A., Rohrer, Jonathan D., Mackenzie, Ian R., Neumann, Manuela, Authier, Astrid, Seelaar, Harro, Van Swieten, John C., Brown, Jeremy M., Johannsen, Peter, Nielsen, Jorgen E., Holm, Ida E., Dickson, Dennis W., Rademakers, Rosa, Graff-Radford, Neill R., Parisi, Joseph E., Petersen, Ronald C., Hatanpaa, Kimmo J., White III, Charles L., Weiner, Myron F., Geser, Felix, Van Deerlin, Vivianna M., Trojanowski, John Q., Miller, Bruce L., Seeley, William W., van der Zee, Julie, Kumar-Singh, Samir, Engelborghs, Sebastiaan, De Deyn, Peter P., Van Broeckhoven, Christine, Bigio, Eileen H., Deng, Han-Xiang, Halliday, Glenda M., Kril, Jillian J., Munoz, David G., Mann, David M., Pickering-Brown, Stuart M., Doodeman, Valerie, Adamson, Gary, Ghazi-Noori, Shabnam, Fisher, Elizabeth M. C., Holton, Janice L., Revesz, Tamas, Rossor, Martin N., Collinge, John, Mead, Simon, Isaacs, Adrian M.
Published 2010

Genetic and Clinical Features of Progranulin-Associated Frontotemporal Lobar Degeneration

by Chen-Plotkin, Alice S., Martinez-Lage, Maria, Sleiman, Patrick M. A., Hu, William, Greene, Robert, Wood, Elisabeth McCarty, Bing, Shaoxu, Grossman, Murray, Schellenberg, Gerard D., Hatanpaa, Kimmo J., Weiner, Myron F., White, Charles L., Brooks, William S., Halliday, Glenda M., Kril, Jillian J., Gearing, Marla, Beach, Thomas G., Graff-Radford, Neill R., Dickson, Dennis W., Rademakers, Rosa, Boeve, Bradley F., Pickering-Brown, Stuart M., Snowden, Julie, van Swieten, John C., Heutink, Peter, Seelaar, Harro, Murrell, Jill R., Ghetti, Bernardino, Spina, Salvatore, Grafman, Jordan, Kaye, Jeffrey A., Woltjer, Randall L., Mesulam, Marsel, Bigio, Eileen, Lladó, Albert, Miller, Bruce L., Alzualde, Ainhoa, Moreno, Fermin, Rohrer, Jonathan D., Mackenzie, Ian R. A., Feldman, Howard H., Hamilton, Ronald L., Cruts, Marc, Engelborghs, Sebastiaan, De Deyn, Peter P., Van Broeckhoven, Christine, Bird, Thomas D., Cairns, Nigel J., Goate, Allison, Frosch, Matthew P., Riederer, Peter F., Bogdanovic, Nenad, Lee, Virginia M. Y., Trojanowski, John Q., Van Deerlin, Vivianna M.
Published 2011

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

by Van Deerlin, Vivianna M., Sleiman, Patrick M. A., Martinez-Lage, Maria, Chen-Plotkin, Alice, Wang, Li-San, Graff-Radford, Neill R, Dickson, Dennis W., Rademakers, Rosa, Boeve, Bradley F., Grossman, Murray, Arnold, Steven E., Mann, David M.A., Pickering-Brown, Stuart M., Seelaar, Harro, Heutink, Peter, van Swieten, John C., Murrell, Jill R., Ghetti, Bernardino, Spina, Salvatore, Grafman, Jordan, Hodges, John, Spillantini, Maria Grazia, Gilman, Sid', Lieberman, Andrew P., Kaye, Jeffrey A., Woltjer, Randall L., Bigio, Eileen H, Mesulam, Marsel, al-Sarraj, Safa, Troakes, Claire, Rosenberg, Roger N., White, Charles L., Ferrer, Isidro, Lladó, Albert, Neumann, Manuela, Kretzschmar, Hans A., Hulette, Christine Marie, Welsh-Bohmer, Kathleen A., Miller, Bruce L, Alzualde, Ainhoa, de Munain, Adolfo Lopez, McKee, Ann C., Gearing, Marla, Levey, Allan I., Lah, James J., Hardy, John, Rohrer, Jonathan D., Lashley, Tammaryn, Mackenzie, Ian R.A., Feldman, Howard H., Hamilton, Ronald L., Dekosky, Steven T., van der Zee, Julie, Kumar-Singh, Samir, Van Broeckhoven, Christine, Mayeux, Richard, Vonsattel, Jean Paul G., Troncoso, Juan C., Kril, Jillian J, Kwok, John B.J., Halliday, Glenda M., Bird, Thomas D., Ince, Paul G., Shaw, Pamela J., Cairns, Nigel J., Morris, John C., McLean, Catriona Ann, DeCarli, Charles, Ellis, William G., Freeman, Stefanie H., Frosch, Matthew P., Growdon, John H., Perl, Daniel P., Sano, Mary, Bennett, David A., Schneider, Julie A., Beach, Thomas G., Reiman, Eric M., Woodruff, Bryan K., Cummings, Jeffrey, Vinters, Harry V., Miller, Carol A., Chui, Helena C., Alafuzoff, Irina, Hartikainen, Päivi, Seilhean, Danielle, Galasko, Douglas, Masliah, Eliezer, Cotman, Carl W., Tuñón, M. Teresa, Martínez, M. Cristina Caballero, Munoz, David G., Carroll, Steven L., Marson, Daniel, Riederer, Peter F., Bogdanovic, Nenad, Schellenberg, Gerard D., Hakonarson, Hakon, Trojanowski, John Q., Lee, Virginia M.-Y.
Published 2010