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The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43
Alzheimer’s disease (AD) is a neurodegenerative condition, of which one of the cardinal pathological hallmarks is the extracellular accumulation of amyloid β (Aβ) peptides. These peptides are generated via proteolysis of the amyloid precursor protein (APP), in a manner dependent on the β-secretase,...
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| Publicado no: | Biosci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7189496/ https://ncbi.nlm.nih.gov/pubmed/32301481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20200435 |
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