Multiple distinct pathways lead to hyperubiquitylated insoluble TDP-43 protein independent of its translocation into stress granules

Παρόμοια τεκμήρια

• Identification and characterization of ubiquitinylation sites in TAR DNA-binding protein of 43 kDa (TDP-43)
  ανά: Hans, Friederike, κ.ά.
  Έκδοση: (2018)
• Cytoplasmic TDP-43 de-mixing independent of stress granules drives inhibition of nuclear import, loss of nuclear TDP-43, and cell death
  ανά: Gasset-Rosa, Fatima, κ.ά.
  Έκδοση: (2019)
• Aggregation of the nucleic acid–binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation
  ανά: Chen, Youjun, κ.ά.
  Έκδοση: (2019)
• TDP-43 Aggregation In Neurodegeneration: Are Stress Granules The Key?
  ανά: Dewey, Colleen M., κ.ά.
  Έκδοση: (2012)
• Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice
  ανά: Beel, Sander, κ.ά.
  Έκδοση: (2018)