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TDP-43 Aggregation In Neurodegeneration: Are Stress Granules The Key?
The RNA-binding protein TDP-43 is strongly linked to neurodegeneration. Not only are mutations in the gene encoding TDP-43 associated with ALS and FTLD, but this protein is also a major constituent of pathological intracellular inclusions in these diseases. Recent studies have significantly expanded...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372581/ https://ncbi.nlm.nih.gov/pubmed/22405725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.02.032 |
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