TDP-43 Is a Developmentally Regulated Protein Essential for Early Embryonic Development

TDP-43 is a DNA/RNA-binding protein implicated in multiple steps of transcriptional and post-transcriptional regulation of gene expression. Alteration of this multifunctional protein is associated with a number of neurodegenerative diseases including amyotrophic lateral sclerosis and frontotemporal...

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Hlavní autoři: Sephton, Chantelle F., Good, Shannon K., Atkin, Stan, Dewey, Colleen M., Mayer, Paul, Herz, Joachim, Yu, Gang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Neurobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825476/
https://ncbi.nlm.nih.gov/pubmed/20040602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061846
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