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Identification and characterization of ubiquitinylation sites in TAR DNA-binding protein of 43 kDa (TDP-43)

TAR DNA-binding protein of 43 kDa (TDP-43) forms pathological aggregates in neurodegenerative diseases, particularly in certain forms of frontotemporal dementia and amyotrophic lateral sclerosis. Pathological modifications of TDP-43 include proteolytic fragmentation, phosphorylation, and ubiquitinyl...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Hans, Friederike, Eckert, Marita, von Zweydorf, Felix, Gloeckner, Christian Johannes, Kahle, Philipp J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187624/
https://ncbi.nlm.nih.gov/pubmed/30120199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003440
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