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Identification and characterization of ubiquitinylation sites in TAR DNA-binding protein of 43 kDa (TDP-43)
TAR DNA-binding protein of 43 kDa (TDP-43) forms pathological aggregates in neurodegenerative diseases, particularly in certain forms of frontotemporal dementia and amyotrophic lateral sclerosis. Pathological modifications of TDP-43 include proteolytic fragmentation, phosphorylation, and ubiquitinyl...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6187624/ https://ncbi.nlm.nih.gov/pubmed/30120199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003440 |
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