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The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43

Alzheimer’s disease (AD) is a neurodegenerative condition, of which one of the cardinal pathological hallmarks is the extracellular accumulation of amyloid β (Aβ) peptides. These peptides are generated via proteolysis of the amyloid precursor protein (APP), in a manner dependent on the β-secretase,...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Biosci Rep
Asıl Yazarlar: Hicks, David A., Jones, Alys C., Pickering-Brown, Stuart M., Hooper, Nigel M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press Ltd. 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189496/
https://ncbi.nlm.nih.gov/pubmed/32301481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20200435
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