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Presenilin-dependent intramembrane cleavage of ephrin-B1
BACKGROUND: Presenilin-dependent γ-secretase cleavage of several transmembrane proteins, including amyloid-β precursor protein and Notch, mediates the intramembrane proteolysis to liberate their intracellular domains that are involved in cellular signaling. Considering γ-secretase inhibitors as ther...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1513130/ https://ncbi.nlm.nih.gov/pubmed/16930449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-1-2 |
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