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Ku70 Alleviates Neurodegeneration in Drosophila Models of Huntington's Disease

DNA damage accumulates in genome DNA during the long life of neurons, thus DNA damage repair is indispensable to keep normal functions of neurons. We previously reported that Ku70, a critical molecule for DNA double strand break (DSB) repair, is involved in the pathology of Huntington's disease...

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Detalhes bibliográficos
Main Authors: Tamura, Takuya, Sone, Masaki, Iwatsubo, Takeshi, Tagawa, Kazuhiko, Wanker, Erich E., Okazawa, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210167/
https://ncbi.nlm.nih.gov/pubmed/22096569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027408
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