The Induction Levels of Heat Shock Protein 70 Differentiate the Vulnerabilities to Mutant Huntingtin among Neuronal Subtypes

The reason why vulnerabilities to mutant polyglutamine (polyQ) proteins are different among neuronal subtypes is mostly unknown. In this study, we compared the gene expression profiles of three types of primary neurons expressing huntingtin (htt) or ataxin-1. We found that heat shock protein 70 (hsp...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Tagawa, Kazuhiko, Marubuchi, Shigeki, Qi, Mei-Ling, Enokido, Yasushi, Tamura, Takuya, Inagaki, Reina, Murata, Miho, Kanazawa, Ichiro, Wanker, Erich E., Okazawa, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672912/
https://ncbi.nlm.nih.gov/pubmed/17251428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4522-06.2007
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