The Induction Levels of Heat Shock Protein 70 Differentiate the Vulnerabilities to Mutant Huntingtin among Neuronal Subtypes

The reason why vulnerabilities to mutant polyglutamine (polyQ) proteins are different among neuronal subtypes is mostly unknown. In this study, we compared the gene expression profiles of three types of primary neurons expressing huntingtin (htt) or ataxin-1. We found that heat shock protein 70 (hsp...

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Publicado en:J Neurosci
Autores principales: Tagawa, Kazuhiko, Marubuchi, Shigeki, Qi, Mei-Ling, Enokido, Yasushi, Tamura, Takuya, Inagaki, Reina, Murata, Miho, Kanazawa, Ichiro, Wanker, Erich E., Okazawa, Hitoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2007
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672912/
https://ncbi.nlm.nih.gov/pubmed/17251428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4522-06.2007
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