Triple mode of action of flecainide in catecholaminergic polymorphic ventricular tachycardia

অনুযায়ী Steele, Derek S., Hwang, Hyun-Seok, Knollmann, Björn C.
প্রকাশিত 2013

Accelerated junctional rhythm and non-alternans repolarization lability precede ventricular tachycardia in Casq2−/− mice

অনুযায়ী Mezu, Ure, Singh, Prabhpreet, Shusterman, Vladimir, Hwang, Hyun Seok, Knollmann, Bjorn C., Němec, Jan
প্রকাশিত 2012

Efficacy of Flecainide in Catecholaminergic Polymorphic Ventricular Tachycardia Is Mutation-Independent but Reduced by Calcium Overload

অনুযায়ী Hwang, Hyun Seok, Baldo, Marcelo P., Rodriguez, Jose Pindado, Faggioni, Michela, Knollmann, Bjorn C.
প্রকাশিত Front Physiol (2019)

Parameter Sensitivity Analysis of Stochastic Models Provides Insights into Cardiac Calcium Sparks

অনুযায়ী Lee, Young-Seon, Liu, Ona Z., Hwang, Hyun Seok, Knollmann, Bjorn C., Sobie, Eric A.
প্রকাশিত 2013

Inhibition of Cardiac Ca(2+) Release Channels (RyR2) Determines Efficacy of Class I Antiarrhythmic Drugs in Catecholaminergic Polymorphic Ventricular Tachycardia

অনুযায়ী Hwang, Hyun Seok, Hasdemir, Can, Laver, Derek, Mehra, Divya, Turhan, Kutsal, Faggioni, Michela, Yin, Huiyong, Knollmann, Björn C.
প্রকাশিত 2011

Suppression of Spontaneous Ca Elevations Prevents Atrial Fibrillation in Casq2 Null Hearts

অনুযায়ী Faggioni, Michela, Savio-Galimberti, Eleonora, Venkataraman, Raghav, Hwang, Hyun-Seok, Kannankeril, Prince J., Darbar, Dawood, Knollmann, Björn C.
প্রকাশিত 2014

Myofilament Ca sensitization increases cytosolic Ca binding affinity, alters intracellular Ca homeostasis and causes pause-dependent Ca triggered arrhythmia

অনুযায়ী Schober, Tilmann, Huke, Sabine, Venkataraman, Raghav, Gryshchenko, Oleksiy, Kryshtal, Dmytro, Hwang, Hyun-Seok, Baudenbacher, Franz J., Knollmann, Björn C.
প্রকাশিত 2012

Myofilament calcium de-sensitization and contractile uncoupling prevents pause-triggered ventricular tachycardia in mouse hearts with chronic myocardial infarction

অনুযায়ী Venkataraman, Raghav, Baldo, Marcelo Perim, Hwang, Hyun-Seok, Veltri, Tiago, Pinto, Jose Renato, Baudenbacher, Franz J., Knollmann, Bjorn C.
প্রকাশিত 2013

SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence

অনুযায়ী Salazar, Gloria, Cullen, Abigail, Huang, Jingwen, Zhao, Yitong, Serino, Alexa, Hilenski, Lula, Patrushev, Nikolay, Forouzandeh, Farshad, Hwang, Hyun Seok
প্রকাশিত Autophagy (2019)

Functional consequences of stably expressing a mutant calsequestrin (CASQ2(D307H)) in the CASQ2 null background

অনুযায়ী Kalyanasundaram, Anuradha, Viatchenko-Karpinski, Serge, Belevych, Andriy E., Lacombe, Veronique A., Hwang, Hyun Seok, Knollmann, Björn C., Gyorke, Sandor, Periasamy, Muthu
প্রকাশিত 2012

Accelerated Sinus Rhythm Prevents Catecholaminergic Polymorphic Ventricular Tachycardia in Mice and in Patients

অনুযায়ী Faggioni, Michela, Hwang, Hyun Seok, van der Werf, Christian, Nederend, Ineke, Kannankeril, Prince J., Wilde, Arthur A.M., Knollmann, Björn C.
প্রকাশিত 2013

Coordinated Regulation of Murine Cardiomyocyte Contractility by Nanomolar (−)-Epigallocatechin-3-Gallate, the Major Green Tea Catechin

অনুযায়ী Feng, Wei, Hwang, Hyun Seok, Kryshtal, Dmytro O., Yang, Tao, Padilla, Isela T., Tiwary, Asheesh K., Puschner, Birgit, Pessah, Isaac N., Knollmann, Björn C.
প্রকাশিত 2012

Pathogenic Troponin T Mutants with Opposing Effects on Myofilament Ca(2+) Sensitivity Attenuate Cardiomyopathy Phenotypes in Mice

অনুযায়ী Jones, Karissa M. Dieseldorff, Koh, Yeojung, Weller, Rebecca S., Turna, Rajdeep S., Ahmad, Ferhaan, Huke, Sabine, Knollmann, Björn C., Pinto, Jose Renato, Hwang, Hyun Seok
প্রকাশিত Arch Biochem Biophys (2018)

Comparable Calcium Handling Of Human iPSC-derived Cardiomyocytes Generated By Multiple Laboratories

অনুযায়ী Hwang, Hyun Seok, Kryshtal, Dmytro O., Feaster, Tromondae K., Sánchez-Freire, Verónica, Zhang, Jianhua, Kamp, Timothy J., Hong, Charles C., Wu, Joseph C., Knollmann, Björn C.
প্রকাশিত J Mol Cell Cardiol (2015)

Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans

অনুযায়ী Watanabe, Hiroshi, Chopra, Nagesh, Laver, Derek, Hwang, Hyun Seok, Davies, Sean S, Roach, Daniel E, Duff, Henry J, Roden, Dan M, Wilde, Arthur A M, Knollmann, Björn C
প্রকাশিত 2009

Divergent Regulation of Ryr2 Calcium Release Channels by Arrhythmogenic Human Calmodulin Missense Mutants

অনুযায়ী Hwang, Hyun-Seok, Nitu, Florentin R, Yang, Yi, Walweel, Kafa, Pereira, Laetitia, Johnson, Christopher N, Faggioni, Michela, Chazin, Walter J, Laver, Derek, George, Alfred L, Cornea, Razvan L, Bers, Donald M, Knollmann, Björn C
প্রকাশিত 2014

Ryanodine receptor inhibition potentiates the activity of Na channel blockers against spontaneous calcium elevations and delayed afterdepolarizations in Langendorff-perfused rabbit...

অনুযায়ী Lee, Young Soo, Maruyama, Mitsunori, Chang, Po Cheng, Park, Hyung Wook, Rhee, Kyoung-Suk, Hsieh, Yu-Cheng, Hsueh, Chia-Hsiang, Shen, Changyu, Lin, Shien-Fong, Hwang, Hyun Seok, Yin, Huiyong, Knollmann, Björn C., Chen, Peng-Sheng
প্রকাশিত 2012

Spectrum and Prevalence of CALM1-, CALM2-, and CALM3-Encoded Calmodulin (CaM) Variants in Long QT Syndrome (LQTS) and Functional Characterization of a Novel LQTS-Associated CaM Mis...

অনুযায়ী Boczek, Nicole J., Gomez-Hurtado, Nieves, Ye, Dan, Calvert, Melissa L., Tester, David J., Kryshtal, Dmytro, Hwang, Hyun Seok, Johnson, Christopher N., Chazin, Walter J., Loporcaro, Christina G., Shah, Maully, Papez, Andrew L., Lau, Yung R., Kanter, Ronald, Knollmann, Bjorn C., Ackerman, Michael J.
প্রকাশিত Circ Cardiovasc Genet (2016)