Functional consequences of stably expressing a mutant calsequestrin (CASQ2(D307H)) in the CASQ2 null background

The role of calsequestrin (CASQ2) in cardiac sarcoplasmic reticulum (SR) calcium (Ca(2+)) transport has gained significant attention since point mutations in CASQ2 were reported to cause ventricular arrhythmia. In the present study, we have critically evaluated the functional consequences of express...

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Détails bibliographiques
Auteurs principaux: Kalyanasundaram, Anuradha, Viatchenko-Karpinski, Serge, Belevych, Andriy E., Lacombe, Veronique A., Hwang, Hyun Seok, Knollmann, Björn C., Gyorke, Sandor, Periasamy, Muthu
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2012
Sujets:
Cardiac Excitation and Contraction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334241/
https://ncbi.nlm.nih.gov/pubmed/21984545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00578.2011
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