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Parameter Sensitivity Analysis of Stochastic Models Provides Insights into Cardiac Calcium Sparks
We present a parameter sensitivity analysis method that is appropriate for stochastic models, and we demonstrate how this analysis generates experimentally testable predictions about the factors that influence local Ca(2+) release in heart cells. The method involves randomly varying all parameters,...
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| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Biophysical Society
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3870797/ https://ncbi.nlm.nih.gov/pubmed/23473497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.055 |
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