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Recovery of cardiac calcium release is controlled by sarcoplasmic reticulum refilling and ryanodine receptor sensitivity

AIMS: In heart cells, the mechanisms underlying refractoriness of the elementary units of sarcoplasmic reticulum (SR) Ca(2+) release, Ca(2+) sparks, remain unclear. We investigated local recovery of SR Ca(2+) release using experimental measurements and mathematical modelling. METHODS AND RESULTS: Re...

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Bibliografiset tiedot
Päätekijät: Ramay, Hena R., Liu, Ona Z., Sobie, Eric A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156908/
https://ncbi.nlm.nih.gov/pubmed/21613275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr143
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