Positive-unlabeled ensemble learning for kinase substrate prediction from dynamic phosphoproteomics data

Por Yang, Pengyi, Humphrey, Sean J., James, David E., Yang, Yee Hwa, Jothi, Raja
Publicado no Bioinformatics (2016)

Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion

Por Sacco, Francesca, Humphrey, Sean J., Cox, Jürgen, Mischnik, Marcel, Schulte, Anke, Klabunde, Thomas, Schäfer, Matthias, Mann, Matthias
Publicado no Nat Commun (2016)

Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2

Por Humphrey, Sean J., Yang, Guang, Yang, Pengyi, Fazakerley, Daniel J., Stöckli, Jacqueline, Yang, Jean Y., James, David E.
Publicado em 2013

KinasePA: Phosphoproteomics data annotation using hypothesis driven kinase perturbation analysis

Por Yang, Pengyi, Patrick, Ellis, Humphrey, Sean J., Ghazanfar, Shila, James, David E., Jothi, Raja, Yang, Jean Yee Hwa
Publicado no Proteomics (2016)

TBC1D13 IS A RAB35 SPECIFIC GAP THAT PLAYS AN IMPORTANT ROLE IN GLUT4 TRAFFICKING IN ADIPOCYTES

Por Davey, Jonathan R, Humphrey, Sean J, Junutula, Jagath R, Mishra, Ashwini K, Lambright, David G, James, David E, Stöckli, Jacqueline
Publicado em 2012

Proteomic Analysis of Human Plasma during Intermittent Fasting

Por Harney, Dylan J., Hutchison, Amy T., Hatchwell, Luke, Humphrey, Sean J., James, David E., Hocking, Samantha, Heilbronn, Leonie K., Larance, Mark
Publicado no J Proteome Res (2019)

Mechanism of Regulation of Intrachromatid Recombination and Long-Range Chromosome Interactions in Saccharomyces cerevisiae

Por Zaman, Shamsu, Choudhury, Malay, Jiang, James C., Srivastava, Pankaj, Mohanty, Bidyut K., Danielson, Christopher, Humphrey, Sean J., Jazwinski, S. Michal, Bastia, Deepak
Publicado no Mol Cell Biol (2016)

RagC phosphorylation autoregulates mTOR complex 1

Por Yang, Guang, Humphrey, Sean J, Murashige, Danielle S, Francis, Deanne, Wang, Qiao‐Ping, Cooke, Kristen C, Neely, G Gregory, James, David E
Publicado no EMBO J (2018)

Correction: Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies

Por Domanova, Westa, Krycer, James R., Chaudhuri, Rima, Yang, Pengyi, Vafaee, Fatemeh, Fazakerley, Daniel J., Humphrey, Sean J., James, David E., Kuncic, Zdenka
Publicado no PLoS One (2017)

ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation

Por Stöckli, Jacqueline, Zadoorian, Armella, Cooke, Kristen C., Deshpande, Vinita, Yau, Belinda, Herrmann, Gaia, Kebede, Melkam A., Humphrey, Sean J., James, David E.
Publicado no Mol Metab (2019)

Insulin Tolerance Test under Anaesthesia to Measure Tissue-specific Insulin-stimulated Glucose Disposal

Por Fazakerley, Daniel J., Fritzen, Andreas M., Nelson, Marin E., Thorius, Ida H., Cooke, Kristen C., Humphrey, Sean J., Cooney, Gregory J., James, David E.
Publicado no Bio Protoc (2019)

PhosphOrtholog: a web-based tool for cross-species mapping of orthologous protein post-translational modifications

Por Chaudhuri, Rima, Sadrieh, Arash, Hoffman, Nolan J., Parker, Benjamin L., Humphrey, Sean J., Stöckli, Jacqueline, Hill, Adam P., James, David E., Yang, Jean Yee Hwa
Publicado no BMC Genomics (2015)

mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes

Por Minard, Annabel Y., Tan, Shi-Xiong, Yang, Pengyi, Fazakerley, Daniel J., Domanova, Westa, Parker, Benjamin L., Humphrey, Sean J., Jothi, Raja, Stöckli, Jacqueline, James, David E.
Publicado no Cell Rep (2016)

A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans

Por Halova, Lenka, Cobley, David, Franz-Wachtel, Mirita, Wang, Tingting, Morrison, Kaitlin R., Krug, Karsten, Nalpas, Nicolas, Maček, Boris, Hagan, Iain M., Humphrey, Sean J., Petersen, Janni
Publicado no Open Biol (2021)

Multi-Omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency

Por Yang, Pengyi, Humphrey, Sean J., Cinghu, Senthilkumar, Pathania, Rajneesh, Oldfield, Andrew J., Kumar, Dhirendra, Perera, Dinuka, Yang, Jean Y.H., James, David E., Mann, Matthias, Jothi, Raja
Publicado no Cell Syst (2019)

Transcriptional network dynamics during the progression of pluripotency revealed by integrative statistical learning

Por Kim, Hani Jieun, Osteil, Pierre, Humphrey, Sean J, Cinghu, Senthilkumar, Oldfield, Andrew J, Patrick, Ellis, Wilkie, Emilie E, Peng, Guangdun, Suo, Shengbao, Jothi, Raja, Tam, Patrick P L, Yang, Pengyi
Publicado no Nucleic Acids Res (2020)

Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes

Por Minard, Annabel Y., Wong, Martin K. L., Chaudhuri, Rima, Tan, Shi-Xiong, Humphrey, Sean J., Parker, Benjamin L., Yang, Jean Y., Laybutt, D. Ross, Cooney, Gregory J., Coster, Adelle C. F., Stöckli, Jacqueline, James, David E.
Publicado no J Biol Chem (2016)

Global phosphoproteomic analysis of human skeletal muscle reveals a network of exercise regulated kinases and AMPK substrates

Por Hoffman, Nolan J., Parker, Benjamin L., Chaudhuri, Rima, Fisher-Wellman, Kelsey H., Kleinert, Maximilian, Humphrey, Sean J., Yang, Pengyi, Holliday, Mira, Trefely, Sophie, Fazakerley, Daniel J., Stöckli, Jacqueline, Burchfield, James G., Jensen, Thomas E., Jothi, Raja, Kiens, Bente, Wojtaszewski, Jørgen F.P., Richter, Erik A., James, David E.
Publicado no Cell Metab (2015)

Global redox proteome and phosphoproteome analysis reveals redox switch in Akt

Por Su, Zhiduan, Burchfield, James G., Yang, Pengyi, Humphrey, Sean J., Yang, Guang, Francis, Deanne, Yasmin, Sabina, Shin, Sung-Young, Norris, Dougall M., Kearney, Alison L., Astore, Miro A., Scavuzzo, Jonathan, Fisher-Wellman, Kelsey H., Wang, Qiao-Ping, Parker, Benjamin L., Neely, G. Gregory, Vafaee, Fatemeh, Chiu, Joyce, Yeo, Reichelle, Hogg, Philip J., Fazakerley, Daniel J., Nguyen, Lan K., Kuyucak, Serdar, James, David E.
Publicado no Nat Commun (2019)

Insulin signaling requires glucose to promote lipid anabolism in adipocytes

Por Krycer, James R., Quek, Lake-Ee, Francis, Deanne, Zadoorian, Armella, Weiss, Fiona C., Cooke, Kristen C., Nelson, Marin E., Diaz-Vegas, Alexis, Humphrey, Sean J., Scalzo, Richard, Hirayama, Akiyoshi, Ikeda, Satsuki, Shoji, Futaba, Suzuki, Kumi, Huynh, Kevin, Giles, Corey, Varney, Bianca, Nagarajan, Shilpa R., Hoy, Andrew J., Soga, Tomoyoshi, Meikle, Peter J., Cooney, Gregory J., Fazakerley, Daniel J., James, David E.
Publicado no J Biol Chem (2020)