Insulin signaling requires glucose to promote lipid anabolism in adipocytes

Adipose tissue is essential for metabolic homeostasis, balancing lipid storage and mobilization based on nutritional status. This is coordinated by insulin, which triggers kinase signaling cascades to modulate numerous metabolic proteins, leading to increased glucose uptake and anabolic processes li...

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Vydáno v:J Biol Chem
Hlavní autoři: Krycer, James R., Quek, Lake-Ee, Francis, Deanne, Zadoorian, Armella, Weiss, Fiona C., Cooke, Kristen C., Nelson, Marin E., Diaz-Vegas, Alexis, Humphrey, Sean J., Scalzo, Richard, Hirayama, Akiyoshi, Ikeda, Satsuki, Shoji, Futaba, Suzuki, Kumi, Huynh, Kevin, Giles, Corey, Varney, Bianca, Nagarajan, Shilpa R., Hoy, Andrew J., Soga, Tomoyoshi, Meikle, Peter J., Cooney, Gregory J., Fazakerley, Daniel J., James, David E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504926/
https://ncbi.nlm.nih.gov/pubmed/32723868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014907
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