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Dynamic (13)C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin
Cellular metabolism is dynamic, but quantifying non-steady metabolic fluxes by stable isotope tracers presents unique computational challenges. Here, we developed an efficient (13)C-tracer dynamic metabolic flux analysis (13C-DMFA) framework for modeling central carbon fluxes that vary over time. We...
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| Pubblicato in: | iScience |
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| Autori principali: | , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7005519/ https://ncbi.nlm.nih.gov/pubmed/32058966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100855 |
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