Positive-unlabeled ensemble learning for kinase substrate prediction from dynamic phosphoproteomics data

по Yang, Pengyi, Humphrey, Sean J., James, David E., Yang, Yee Hwa, Jothi, Raja
Опубликовано в: Bioinformatics (2016)

Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion

по Sacco, Francesca, Humphrey, Sean J., Cox, Jürgen, Mischnik, Marcel, Schulte, Anke, Klabunde, Thomas, Schäfer, Matthias, Mann, Matthias
Опубликовано в: Nat Commun (2016)

Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2

по Humphrey, Sean J., Yang, Guang, Yang, Pengyi, Fazakerley, Daniel J., Stöckli, Jacqueline, Yang, Jean Y., James, David E.
Опубликовано 2013

KinasePA: Phosphoproteomics data annotation using hypothesis driven kinase perturbation analysis

по Yang, Pengyi, Patrick, Ellis, Humphrey, Sean J., Ghazanfar, Shila, James, David E., Jothi, Raja, Yang, Jean Yee Hwa
Опубликовано в: Proteomics (2016)

TBC1D13 IS A RAB35 SPECIFIC GAP THAT PLAYS AN IMPORTANT ROLE IN GLUT4 TRAFFICKING IN ADIPOCYTES

по Davey, Jonathan R, Humphrey, Sean J, Junutula, Jagath R, Mishra, Ashwini K, Lambright, David G, James, David E, Stöckli, Jacqueline
Опубликовано 2012

Proteomic Analysis of Human Plasma during Intermittent Fasting

по Harney, Dylan J., Hutchison, Amy T., Hatchwell, Luke, Humphrey, Sean J., James, David E., Hocking, Samantha, Heilbronn, Leonie K., Larance, Mark
Опубликовано в: J Proteome Res (2019)

Mechanism of Regulation of Intrachromatid Recombination and Long-Range Chromosome Interactions in Saccharomyces cerevisiae

по Zaman, Shamsu, Choudhury, Malay, Jiang, James C., Srivastava, Pankaj, Mohanty, Bidyut K., Danielson, Christopher, Humphrey, Sean J., Jazwinski, S. Michal, Bastia, Deepak
Опубликовано в: Mol Cell Biol (2016)

RagC phosphorylation autoregulates mTOR complex 1

по Yang, Guang, Humphrey, Sean J, Murashige, Danielle S, Francis, Deanne, Wang, Qiao‐Ping, Cooke, Kristen C, Neely, G Gregory, James, David E
Опубликовано в: EMBO J (2018)

Correction: Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies

по Domanova, Westa, Krycer, James R., Chaudhuri, Rima, Yang, Pengyi, Vafaee, Fatemeh, Fazakerley, Daniel J., Humphrey, Sean J., James, David E., Kuncic, Zdenka
Опубликовано в: PLoS One (2017)

ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation

по Stöckli, Jacqueline, Zadoorian, Armella, Cooke, Kristen C., Deshpande, Vinita, Yau, Belinda, Herrmann, Gaia, Kebede, Melkam A., Humphrey, Sean J., James, David E.
Опубликовано в: Mol Metab (2019)

Corrigendum to ‘ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation’ [Molecular Metabolism 25 (2019) p.83–94]

по Stöckli, Jacqueline, Zadoorian, Armella, Cooke, Kristen C., Deshpande, Vinita, Yau, Belinda, Herrmann, Gaia, Kebede, Melkam A., Humphrey, Sean J., James, David E.
Опубликовано в: Mol Metab (2021)

Insulin Tolerance Test under Anaesthesia to Measure Tissue-specific Insulin-stimulated Glucose Disposal

по Fazakerley, Daniel J., Fritzen, Andreas M., Nelson, Marin E., Thorius, Ida H., Cooke, Kristen C., Humphrey, Sean J., Cooney, Gregory J., James, David E.
Опубликовано в: Bio Protoc (2019)

PhosphOrtholog: a web-based tool for cross-species mapping of orthologous protein post-translational modifications

по Chaudhuri, Rima, Sadrieh, Arash, Hoffman, Nolan J., Parker, Benjamin L., Humphrey, Sean J., Stöckli, Jacqueline, Hill, Adam P., James, David E., Yang, Jean Yee Hwa
Опубликовано в: BMC Genomics (2015)

A Two-Dimensional Metallacycle Cross-Linked Switchable Polymer for Fast and Highly Efficient Phosphorylated Peptide Enrichment

по Chen, Li-Jun, Humphrey, Sean J., Zhu, Jun-Long, Zhu, Fan-Fan, Wang, Xu-Qing, Wang, Xiang, Wen, Jin, Yang, Hai-Bo, Gale, Philip A.
Опубликовано в: J Am Chem Soc (2021)

mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes

по Minard, Annabel Y., Tan, Shi-Xiong, Yang, Pengyi, Fazakerley, Daniel J., Domanova, Westa, Parker, Benjamin L., Humphrey, Sean J., Jothi, Raja, Stöckli, Jacqueline, James, David E.
Опубликовано в: Cell Rep (2016)

A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans

по Halova, Lenka, Cobley, David, Franz-Wachtel, Mirita, Wang, Tingting, Morrison, Kaitlin R., Krug, Karsten, Nalpas, Nicolas, Maček, Boris, Hagan, Iain M., Humphrey, Sean J., Petersen, Janni
Опубликовано в: Open Biol (2021)

Multi-Omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency

по Yang, Pengyi, Humphrey, Sean J., Cinghu, Senthilkumar, Pathania, Rajneesh, Oldfield, Andrew J., Kumar, Dhirendra, Perera, Dinuka, Yang, Jean Y.H., James, David E., Mann, Matthias, Jothi, Raja
Опубликовано в: Cell Syst (2019)

Transcriptional network dynamics during the progression of pluripotency revealed by integrative statistical learning

по Kim, Hani Jieun, Osteil, Pierre, Humphrey, Sean J, Cinghu, Senthilkumar, Oldfield, Andrew J, Patrick, Ellis, Wilkie, Emilie E, Peng, Guangdun, Suo, Shengbao, Jothi, Raja, Tam, Patrick P L, Yang, Pengyi
Опубликовано в: Nucleic Acids Res (2020)

Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells

по Recasens, Ariadna, Humphrey, Sean J., Ellis, Michael, Hoque, Monira, Abbassi, Ramzi H., Chen, Brianna, Longworth, Mitchell, Needham, Elise J., James, David E., Johns, Terrance G., Day, Bryan W., Kassiou, Michael, Yang, Pengyi, Munoz, Lenka
Опубликовано в: Cell Death Discov (2021)

Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes

по Minard, Annabel Y., Wong, Martin K. L., Chaudhuri, Rima, Tan, Shi-Xiong, Humphrey, Sean J., Parker, Benjamin L., Yang, Jean Y., Laybutt, D. Ross, Cooney, Gregory J., Coster, Adelle C. F., Stöckli, Jacqueline, James, David E.
Опубликовано в: J Biol Chem (2016)