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Positive-unlabeled ensemble learning for kinase substrate prediction from dynamic phosphoproteomics data

Motivation: Protein phosphorylation is a post-translational modification that underlines various aspects of cellular signaling. A key step to reconstructing signaling networks involves identification of the set of all kinases and their substrates. Experimental characterization of kinase substrates i...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Yang, Pengyi, Humphrey, Sean J., James, David E., Yang, Yee Hwa, Jothi, Raja
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739180/
https://ncbi.nlm.nih.gov/pubmed/26395771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv550
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