Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2

A major challenge of the post-genomics era is to define the connectivity of protein phosphorylation networks. Here, we quantitatively delineate the insulin signaling network in adipocytes by high-resolution mass spectrometry-based proteomics. These data reveal the complexity of intracellular protein...

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Detalhes bibliográficos
Main Authors: Humphrey, Sean J., Yang, Guang, Yang, Pengyi, Fazakerley, Daniel J., Stöckli, Jacqueline, Yang, Jean Y., James, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690479/
https://ncbi.nlm.nih.gov/pubmed/23684622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.04.010
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