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RagC phosphorylation autoregulates mTOR complex 1

The mechanistic (or mammalian) target of rapamycin complex 1 (mTORC1) controls cell growth, proliferation, and metabolism in response to diverse stimuli. Two major parallel pathways are implicated in mTORC1 regulation including a growth factor‐responsive pathway mediated via TSC2/Rheb and an amino a...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Yang, Guang, Humphrey, Sean J, Murashige, Danielle S, Francis, Deanne, Wang, Qiao‐Ping, Cooke, Kristen C, Neely, G Gregory, James, David E
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356064/
https://ncbi.nlm.nih.gov/pubmed/30552228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899548
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