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mTOR signaling: RAG GTPases transmit the amino acid signal

mTOR (mammalian target of rapamycin) is a highly conserved nutrient-responsive regulator of cell growth that is found in all eukaryotes. The mechanism by which amino acids signal to mTOR has remained one of the largest outstanding questions in the field. Two recent complimentary studies provide comp...

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Detalhes bibliográficos
Autor principal: Shaw, Reuben J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677387/
https://ncbi.nlm.nih.gov/pubmed/18929489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2008.09.005
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