Amino Acid Signaling to mTOR Mediated by Inositol Polyphosphate Multikinase

mTOR Complex 1 (mTORC1; mammalian target of rapamycin (mTOR) in complex with raptor) is a key regulator of protein synthesis and cell growth in response to nutrient amino acids. Here we report that inositol polyphosphate multikinase (IPMK), which possesses both inositol phosphate kinase and lipid ki...

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Detalhes bibliográficos
Main Authors: Kim, Seyun, Kim, Sangwon F., Maag, David, Maxwell, Micah J., Resnick, Adam C., Juluri, Krishna R., Chakraborty, Anutosh, Koldobskiy, Michael A., Cha, Seung Hun, Barrow, Roxanne, Snowman, Adele M., Snyder, Solomon H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042716/
https://ncbi.nlm.nih.gov/pubmed/21284988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.01.007
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