ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation

OBJECTIVE: Insulin suppresses adipose tissue lipolysis after a meal, playing a key role in metabolic homeostasis. This is mediated via the kinase Akt and its substrate phosphodiesterase 3B (PDE3B). Once phosphorylated and activated, PDE3B hydrolyses cAMP leading to the inactivation of cAMP-dependent...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Stöckli, Jacqueline, Zadoorian, Armella, Cooke, Kristen C., Deshpande, Vinita, Yau, Belinda, Herrmann, Gaia, Kebede, Melkam A., Humphrey, Sean J., James, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601125/
https://ncbi.nlm.nih.gov/pubmed/31105056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.05.002
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