Regulation of oscillation dynamics in biochemical systems with dual negative feedback loops

Autor Nguyen, Lan K.
Vydáno 2012

On the functional diversity of dynamical behaviour in genetic and metabolic feedback systems

Autor Nguyen, Lan K, Kulasiri, Don
Vydáno 2009

Unveiling Hidden Dynamics of Hippo Signalling: A Systems Analysis

Autor Shin, Sung-Young, Nguyen, Lan K.
Vydáno v Genes (Basel) (2016)

Dynamic modelling of the mTOR signalling network reveals complex emergent behaviours conferred by DEPTOR

Autor Varusai, Thawfeek M., Nguyen, Lan K.
Vydáno v Sci Rep (2018)

Hypoxia-inducible factor (HIF) network: insights from mathematical models

Autor Cavadas, Miguel AS, Nguyen, Lan K, Cheong, Alex
Vydáno 2013

When ubiquitination meets phosphorylation: a systems biology perspective of EGFR/MAPK signalling

Autor Nguyen, Lan K, Kolch, Walter, Kholodenko, Boris N
Vydáno 2013

Rac1 and RhoA: Networks, loops and bistability

Autor Nguyen, Lan K., Kholodenko, Boris N., von Kriegsheim, Alex
Vydáno v Small GTPases (2016)

Polyubiquitin chain assembly and organization determine the dynamics of protein activation and degradation

Autor Nguyen, Lan K., Dobrzyński, Maciej, Fey, Dirk, Kholodenko, Boris N.
Vydáno 2014

DYVIPAC: an integrated analysis and visualisation framework to probe multi-dimensional biological networks

Autor Nguyen, Lan K., Degasperi, Andrea, Cotter, Philip, Kholodenko, Boris N.
Vydáno v Sci Rep (2015)

Feedback, Crosstalk and Competition: Ingredients for Emergent Non-Linear Behaviour in the PI3K/mTOR Signalling Network

Autor Ghomlaghi, Milad, Hart, Anthony, Hoang, Nhan, Shin, Sungyoung, Nguyen, Lan K.
Vydáno v Int J Mol Sci (2021)

Coupled feedback regulation of nuclear factor of activated T-cells (NFAT) modulates activation-induced cell death of T cells

Autor Shin, Sung-Young, Kim, Min-Wook, Cho, Kwang-Hyun, Nguyen, Lan K.
Vydáno v Sci Rep (2019)

Competing to coordinate cell fate decisions: the MST2-Raf-1 signaling device

Autor Nguyen, Lan K, Matallanas, David G, Romano, David, Kholodenko, Boris N, Kolch, Walter
Vydáno v Cell Cycle (2015)

Systems modelling of the EGFR-PYK2-c-Met interaction network predicts and prioritizes synergistic drug combinations for triple-negative breast cancer

Autor Shin, Sung-Young, Müller, Anna-Katharina, Verma, Nandini, Lev, Sima, Nguyen, Lan K.
Vydáno v PLoS Comput Biol (2018)

Signalling by protein phosphatases and drug development: a systems-centred view

Autor Nguyen, Lan K., Matallanas, David, Croucher, David R., von Kriegsheim, Alexander, Kholodenko, Boris N.
Vydáno 2012

Species differential regulation of COX2 can be described by an NFκB-dependent logic AND gate

Autor Nguyen, Lan K., Cavadas, Miguel A. S., Kholodenko, Boris N., Frank, Till D., Cheong, Alex
Vydáno v Cell Mol Life Sci (2015)

Asparagine Hydroxylation is a Reversible Post-translational Modification

Autor Rodriguez, Javier, Haydinger, Cameron D., Peet, Daniel J., Nguyen, Lan K., von Kriegsheim, Alex
Vydáno v Mol Cell Proteomics (2020)

Switches, Excitable Responses and Oscillations in the Ring1B/Bmi1 Ubiquitination System

Autor Nguyen, Lan K., Muñoz-García, Javier, Maccario, Helene, Ciechanover, Aaron, Kolch, Walter, Kholodenko, Boris N.
Vydáno 2011

LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy

Autor Padman, Benjamin Scott, Nguyen, Thanh Ngoc, Uoselis, Louise, Skulsuppaisarn, Marvin, Nguyen, Lan K., Lazarou, Michael
Vydáno v Nat Commun (2019)

MST2-RASSF protein–protein interactions through SARAH domains

Autor Sánchez-Sanz, Goar, Matallanas, David, Nguyen, Lan K., Kholodenko, Boris N., Rosta, Edina, Kolch, Walter, Buchete, Nicolae-Viorel
Vydáno v Brief Bioinform (2016)

Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responses

Autor Dobrzyński, Maciej, Nguyen, Lan K., Birtwistle, Marc R., von Kriegsheim, Alexander, Blanco Fernández, Alfonso, Cheong, Alex, Kolch, Walter, Kholodenko, Boris N.
Vydáno v J R Soc Interface (2014)