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Signalling by protein phosphatases and drug development: a systems-centred view
Protein-modification cycles catalysed by opposing enzymes, such as kinases and phosphatases form the backbone of signalling networks. Whereas historically, kinases have been at the research forefront, a systems-centred approach reveals predominant roles of phosphatases in controlling the network res...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368988/ https://ncbi.nlm.nih.gov/pubmed/22340367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2012.08522.x |
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