FluxFix: automatic isotopologue normalization for metabolic tracer analysis

Por Trefely, Sophie, Ashwell, Peter, Snyder, Nathaniel W.
Publicado no BMC Bioinformatics (2016)

LC-quadrupole/Orbitrap high resolution mass spectrometry enables stable isotope resolved simultaneous quantification and 13C-isotopic labeling of acyl-Coenzyme A thioesters

Por Frey, Alexander J., Feldman, Daniel R., Trefely, Sophie, Worth, Andrew J., Basu, Sankha S., Snyder, Nathaniel W.
Publicado no Anal Bioanal Chem (2016)

Structural Basis for Phosphorylation and Lysine Acetylation Cross-talk in a Kinase Motif Associated with Myocardial Ischemia and Cardioprotection

Por Parker, Benjamin L., Shepherd, Nicholas E., Trefely, Sophie, Hoffman, Nolan J., White, Melanie Y., Engholm-Keller, Kasper, Hambly, Brett D., Larsen, Martin R., James, David E., Cordwell, Stuart J.
Publicado em 2014

Structural basis for phosphorylation and lysine acetylation cross-talk in a kinase motif associated with myocardial ischemia and cardioprotection.

Por Parker, Benjamin L., Shepherd, Nicholas E., Trefely, Sophie, Hoffman, Nolan J., White, Melanie Y., Engholm-Keller, Kasper, Hambly, Brett D., Larsen, Martin R., James, David E., Cordwell, Stuart J.
Publicado no J Biol Chem (2014)

Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism

Por Shah, Supriya, Carriveau, Whitney J., Li, Jinyang, Campbell, Sydney L., Kopinski, Piotr K., Lim, Hee-Woong, Daurio, Natalie, Trefely, Sophie, Won, Kyoung-Jae, Wallace, Douglas C., Koumenis, Constantinos, Mancuso, Anthony, Wellen, Kathryn E.
Publicado no Oncotarget (2016)

Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway

Por Trefely, Sophie, Khoo, Poh-Sim, Krycer, James R., Chaudhuri, Rima, Fazakerley, Daniel J., Parker, Benjamin L., Sultani, Ghazal, Lee, James, Stephan, Jean-Philippe, Torres, Eric, Jung, Kenneth, Kuijl, Coenraad, James, David E., Junutula, Jagath R., Stöckli, Jacqueline
Publicado no J Biol Chem (2015)

Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels

Por Carrer, Alessandro, Parris, Joshua L. D., Trefely, Sophie, Henry, Ryan A., Montgomery, David C., Torres, AnnMarie, Viola, John M., Kuo, Yin-Ming, Blair, Ian A., Meier, Jordan L., Andrews, Andrew J., Snyder, Nathaniel W., Wellen, Kathryn E.
Publicado no J Biol Chem (2017)

Global phosphoproteomic analysis of human skeletal muscle reveals a network of exercise regulated kinases and AMPK substrates

Por Hoffman, Nolan J., Parker, Benjamin L., Chaudhuri, Rima, Fisher-Wellman, Kelsey H., Kleinert, Maximilian, Humphrey, Sean J., Yang, Pengyi, Holliday, Mira, Trefely, Sophie, Fazakerley, Daniel J., Stöckli, Jacqueline, Burchfield, James G., Jensen, Thomas E., Jothi, Raja, Kiens, Bente, Wojtaszewski, Jørgen F.P., Richter, Erik A., James, David E.
Publicado no Cell Metab (2015)

ATP-citrate lyase controls a glucose-to-acetate metabolic switch

Por Zhao, Steven, Torres, AnnMarie, Henry, Ryan A., Trefely, Sophie, Wallace, Martina, Lee, Joyce V., Carrer, Alessandro, Sengupta, Arjun, Campbell, Sydney L., Kuo, Yin-Ming, Frey, Alexander J., Meurs, Noah, Viola, John M., Blair, Ian A., Weljie, Aalim M., Metallo, Christian M., Snyder, Nathaniel W., Andrews, Andrew J., Wellen, Kathryn E.
Publicado no Cell Rep (2016)