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LC-quadrupole/Orbitrap high resolution mass spectrometry enables stable isotope resolved simultaneous quantification and 13C-isotopic labeling of acyl-Coenzyme A thioesters

Acyl-coenyzme A thioesters (acyl-CoAs) are evolutionarily conserved, compartmentalized, and energetically activated substrates for biochemical reactions. The ubiquitous involvement of acyl-CoAs in metabolism, including the tricarboxylic acid cycle, fatty acid metabolism, amino acid degradation, and...

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Detalles Bibliográficos
Publicado en:Anal Bioanal Chem
Main Authors: Frey, Alexander J., Feldman, Daniel R., Trefely, Sophie, Worth, Andrew J., Basu, Sankha S., Snyder, Nathaniel W.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838547/
https://ncbi.nlm.nih.gov/pubmed/26968563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-016-9448-5
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